Biochemical Basis of Health & Disease

BCHM 270/3.0

This course will introduce general biochemical concepts that will allow for an understanding of the biological and chemical principles underlying human physiology, health and disease. The course will provide self-paced learning and utilize evidence-based teaching principles, small group learning, peer-learning and guided-independent learning methodologies to provide an inclusive learning environment. Students will gain an enhanced appreciation of general applications of biochemistry as applied in day to day healthy life and during the disease states, diagnosis and clinical management of metabolic disorders.

Description

BCHM 270, Biochemical Basis of Health & Disease will introduce general biochemical concepts that will allow for an understanding of the biological and chemical principles underlying human physiology, health and disease. The course will provide collaborative, self-paced learning and utilize evidence-based teaching principles, small group learning, peer-learning, peer-evaluations and guided-independent learning methodologies to provide an inclusive learning environment. Students will come out with an enhanced appreciation of general applications of biochemistry as applied in day to day healthy life and during the disease states, diagnosis and clinical management of metabolic disorders.

This introductory biochemistry online course is intended for prospective students in Nursing, Environmental Sciences, Engineering, Commerce, and general science programs.

Evaluation

Active Learning Activities20%
Term Paper10%
Midterm Quiz20%
Proctored Final Exam50%

Topics

Learning Outcomes

  • Apply knowledge of biological systems and their interactions to explain how the human body functions in health and disease.
  • Gain understanding of major bio-molecules of life at structural level (Proteins, nucleic acids, carbohydrates, lipids, fatty acids, vitamins etc).
  • Apply knowledge of the atomic and molecular characteristics of biological constituents to predict normal and pathological molecular function.
  • Explain how the regulation of major biochemical energy production pathways and the synthesis/degradation of macromolecules function to maintain health and identify major forms of dysregulation in disease.
  • Explain the major mechanisms of intra- and intercellular communication and their role in health and disease states.
  • Use the principles of feedback control to explain how specific homeostatic systems maintain the internal environment and identify (1) how perturbations in these systems may result in disease and (2) how homeostasis may be changed by disease.
  • Apply elements of the scientific process, such as inference, critical analysis of research design, and appreciation of the difference between association and causation, to interpret the findings, applications, and limitations of observational and experimental research in clinical decision making.

Topics

Topics covered in this course include:

Module 1Building Blocks and Energy Systems
Module 2Intermediary Metabolism
Module 3Lipid Metabolism
Module 4Biomolecules that the Body Doesn't Want to Store
Module 5Intergration of Metabolism
Module 6Molecular Basis of Health and Disease

 

Instructor

Portrait of course instructor Dr. Vinay SinghDr. Vinay Singh has over 18 years of proven achievements in Teaching and Research. He is a decorated Professor at Queen’s University with numerous awards in teaching and research. Vinay’s research expertise includes oncology, biochemistry, biotechnology and pre-clinical studies. To date, Vinay has obtained four patents, published over 38 high impact research papers and delivered over 50 conference presentations. Apart from his academic career, Vinay is a seasoned consultant in the biotech and the life sciences space and an expert of new product development. Vinay has a PhD in Biotechnology and an Executive MBA from Queen’s University, Kingston, Canada.

Time Commitment

Students can expect to spend approximately 10 hours a week (120 hours per term) in study/practice and online activity for BCHM 270.

Course Resources

About SOLUS

SOLUS is Queen’s Student On-Line University System. You’ll have access to a SOLUS account once you become a Queen’s student. You’ll use SOLUS to register for courses, add and drop courses, update your contact information, view financial and academic information, and pay your tuition.

About MOODLE

Moodle is Queen's online learning platform. You'll log into Moodle to access your course. All materials related to your course—notes, readings, videos, recordings, discussion forums, assignments, quizzes, groupwork, tutorials, and help—will be on the Moodle site.

About Credit Units

Queen’s courses are weighted in credit units. A typical one-term course is worth 3.0 units, and a typical two-term course is worth 6.0 units. You combine these units to create your degree. A general (three-year) BA requires a total of 90 credit units.

Computer Requirements

To take an online course, you’ll need a good-quality computer (Windows XP/Vista/7, Pentium III, or Mac OS X 10.5, G4 or G5 processor, 256 MB RAM) with a high-speed internet connection, soundcard, speakers, and microphone, and up-to-date versions of free software (Explorer/Firefox, Java, Flash, Adobe Reader). See also Preparing For Your Course.

Dates/Deadlines

The deadlines for new applications to Queen’s Arts and Science Online courses are in our Dates and Deadlines section.

Tuition Fees

Tuition fees vary depending when you start, your year, faculty, and program. Fees for 2014-15 first-year Distance Career Arts & Science Canadian students are as follows: for a 3.0-unit course, $605.31; for a 6.0-unit course, $1210.62. See also Tuition and Payment.

Grading Scheme

The information below is intended for undergraduate students in the Faculty of Arts and Science. Academic Regulations in other Faculties may differ.

Letter Grade Grade Point
A+4.30
A4.00
A-3.70
B+3.30
B3.00
B-2.70
C+2.30
C2.00
C-1.70
D+1.30
D1.00
D-0.70
F0.00

GPA Calculators
Have your SOLUS grade report handy and then follow the link to the Arts and Science GPA calculators.

How does this affect my academics?
See the GPA and Academic Standing page.

Follow the link above for an explanation of how the GPA system affects such things as the Dean’s Honour List, requirements to graduate, and academic progression.

Frequently Asked Questions on the Grading Scheme
Please follow this link to the FAQ's

Campus Bookstore

All textbooks can be purchased at Queen’s Campus Bookstore.

Non-Queen’s Students

All Queen’s Arts and Science Online courses are open to students at other universities. Before applying as a visiting student, request a Letter of Permission from your home university that states that you have permission to take the course and apply it to your degree. See also Apply.

Academic Integrity

Please see Queen’s policy statement on academic integrity for information on how to complete an online course honestly.