Introductory Pharmacology

PHAR 100/3.0

Topics covered include central nervous system stimulants and depressants, narcotics, alcohol,  contraceptives, environmental toxicants, mechanism of drug action and disposition, antibiotics, drugs used in sports, over-the-counter drugs, food additives, and vitamins.

Learning Outcomes

Learning Outcomes

After completing PHAR 100, students will be able to:

  1. Discuss the pharmacological principles of drug abuse to advocate for healthy and appropriate drug use.
  2. Describe the mechanism of action and physiological effects of classes of drugs to be able to summarize the reason(s) for their use and abuse in society.
  3. Apply learned knowledge of the essential elements of a phase 3 clinical trial to design a hypothetical clinical trial for a new drug to treat a specific disease or condition.
  4. Effectively discuss and apply relevant pharmacological principles within a group to successfully complete collaborative assignments.

 

Topics

Section A. Basic Principles of Pharmacology
•    History of Drug Use and Development
•    Drug Development, Drug Trials, and Drug Advertising
•    Drug Action
•    Pharmacokinetics
•    Drug Toxicity and Drug Interactions.


Section B. Drugs of Abuse Part I
•    Physiological and Pharmacological Aspects of the Central Nervous System
•    Substance Abuse and Substance Dependence
•    Stimulant Drugs
•    Drugs Used in Sports


Section C. Drugs of Abuse Part II  
•    Sedative-Hypnotics
•    Alcohol
•    Cannabis (Marijuana)
•    Narcotic Analgesics (Opiates, Opioids)


Section D. Common Prescription Drugs
•    Antibacterial, Antifungal, and Antiviral Agents
•    Regulation of Fertility


Section E. Non-Prescription Drugs and Chemicals
•    Over-the-counter (OTC) Drugs
•    Herbal Remedies
•    Vitamins
•    Food Additives


Section F. Environmental Toxicology
•    Cancer
•    Environment and Health
•    Pharmaceuticals in the Environment

Description

PHAR 100, Introductory Pharmacology, is designed as a general interest course that introduces the subjects of pharmacology and toxicology. Pharmacology is broadly defined as the effect of drugs and chemicals on living organisms, while toxicology is the study of the deleterious effects of drugs and chemicals on living organisms. No prior knowledge of physiology is required to understand the drug action described in this course, as the physiology needed is covered in the course notes and the textbook. This 12-week course consists of six modules. Students will work through the modules online, using a combination of course notes, text book readings and short video clips. Students will participate in two activities throughout the course that will encourage communication and teamwork, as well as ensure concepts have been understood and can be applied to real life scenarios.In addition, students will be required to submit one individual assignment, answering assigned questions about the course material. At the end of the course, students will have a basic understanding of pharmacology and toxicology.

Terms

Winter 2017
Course Dates: 
Jan 9 - Apr 7, 2017
Exam Dates: 
Apr 13 - 27, 2017

Evaluation

Phase III Clinical Trial Poster10%
Online Discussion (marijuana legalization)20%
Individual Assignment20%
Midterm Quiz10%
Final Proctored Exam40%

** Evaluation Subject to Change **

Final Examination

Students must write their exam on the day and time scheduled by the University. The start time may vary slightly depending on the off-campus exam centre. Do not schedule vacations, appointments, etc., during the exam period.

Instructor

Professor William Racz (raczw@queensu.ca) & Professor Jeanne Mulder (jeanne.mulder@queensu.ca)

Time Commitment

Students can expect to spend approximately 10-12 hours/week in study, practice and online activity for PHAR 100.

Fall 2016
Course Dates: 
Sept 12 - Dec 2, 2016
Exam Dates: 
Dec 7 - 21, 2016

Evaluation

Phase III Clinical Trial Poster10%
Online Discussion (marijuana legalization)20%
Individual Assignment20%
Midterm Quiz10%
Final Proctored Exam40%

** Evaluation Subject to Change **

Final Examination

Students must write their exam on the day and time scheduled by the University. The start time may vary slightly depending on the off-campus exam centre. Do not schedule vacations, appointments, etc., during the exam period.

Instructor

Professor William Racz (raczw@queensu.ca) & Professor Jeanne Mulder (jeanne.mulder@queensu.ca)

Time Commitment

Students can expect to spend approximately 10-12 hours/week in study, practice and online activity for PHAR 100.

Summer 16: May - July
Course Dates: 
May 2 - July 22, 2016
Exam Dates: 
July 26 - 29, 2016

Evaluation

Students will be evaluated on two active learning activities (25%), one individual written assignment (15%), one midterm quiz (10%), and a final proctored exam (50%). One of the active learning components will include peer critique. Students will also have multiple opportunities to self-assess their progress through small quizzes.

2 Active Learning Activities25%
Individual Assignment15%
Online Midterm Quiz10%
Final Proctored Exam50%

** Evaluation Subject to Change **

Final Examination

Students must write their exam on the day and time scheduled by the University. The start time may vary slightly depending on the off-campus exam centre. Do not schedule vacations, appointments, etc., during the exam period.

Final Examination Format

The three-hour final exam will consist of multiple-choice questions of the type given as practice questions at the end of each lesson, and four short-answer questions. The multiple-choice questions will be worth 80%, and the short-answer questions worth 20% of the final exam.

Instructor

Professor William Racz (raczw@queensu.ca) and Professor Jeanne Mulder (jeanne.mulder@queensu.ca)

Instructor message

Dr. Racz obtained a Bachelor of Science degree in Pharmacy from the University of Saskatchewan. After three years of practice, he returned to university and obtained a Master’s degree in Medicinal Chemistry and a doctorate in Pharmacology from the University of Alberta. He is currently Professor Emeritus of Pharmacology and Toxicology, School of Medicine, Faculty of Health Sciences, Queen’s University. His interest in educating physicians, nursing science and life science students, and the public in the area of pharmacology and drug use spans almost four decades. His research interests include heavy metal toxicity and drug induced liver injury. He is a past president of the Society of Toxicology of Canada, a consultant to the Committee for The Evaluation of Drugs, Ministry of Health, Ontario and has served on several expert panels.

Dr. Mulder obtained a Bachelor of Science degree in Life Sciences, and Masters and Doctoral degrees in Pharmacology and Toxicology at Queen’s University. Dr. Mulder is currently Adjunct Assistant Professor and Research Associate in the Department of Biomedical and Molecular Sciences at Queen’s University. Her current research interests include environmental toxicants and drug-induced lung and liver toxicities, including cancer. She has been involved with the online version of PHAR100 for over five years and is enthusiastic about teaching pharmacology and toxicology.  

Time Commitment

Students can expect to spend approximately 9 - 10 hours/week in study, practice and online activity for PHAR 100.

Course Resources

About SOLUS

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About OnQ

OnQ is Queen's online learning platform. You'll log into Moodle to access your course. All materials related to your course—notes, readings, videos, recordings, discussion forums, assignments, quizzes, groupwork, tutorials, and help—will be on the OnQ site.

About Credit Units

Queen’s courses are weighted in credit units. A typical one-term course is worth 3.0 units, and a typical two-term course is worth 6.0 units. You combine these units to create your degree. A general (three-year) BA or BSc requires a total of 90 credit units.

Computer Requirements

To take an online course, you’ll need a high speed internet connection as well as a microphone and speakers to be able to watch videos, hear sounds, and participate in interactive online activities. A webcam is recommended but not necessary.

System Requirements:

  • Laptop or Desktop computer purchased within the last 5 years. (mobile devices are not supported)
  • Windows Vista SP2/Mac OSX 10.9 or higher
  • Up to date versions of Firefox, Internet Explorer or Safari. Please note that Google Chrome is not recommended for use in our courses.
  • Most recent version of Adobe Reader and Adobe Flash

 See also Getting Started.

Dates/Deadlines

The deadlines for new applications to Queen’s Arts and Science Online courses are in our Upcoming Application Dates section.

Tuition Fees

Tuition fees vary depending when you start, your year, faculty, and program. Fees for 2016-17 first-year Distance Career Arts & Science Canadian students are as follows: for a 3.0-unit course, $648.40; for a 6.0-unit course, $1296.80. See also Tuition and Fees.

Grading Scheme

The information below is intended for undergraduate students in the Faculty of Arts and Science. Academic Regulations in other Faculties may differ.

Letter Grade Grade Point
A+4.30
A4.00
A-3.70
B+3.30
B3.00
B-2.70
C+2.30
C2.00
C-1.70
D+1.30
D1.00
D-0.70
F0.00

GPA Calculators
Have your SOLUS grade report handy and then follow the link to the Arts and Science GPA calculators.

How does this affect my academics?
See the GPA and Academic Standing page.

Follow the link above for an explanation of how the GPA system affects such things as the Dean’s Honour List, requirements to graduate, and academic progression.

Frequently Asked Questions on the Grading Scheme
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Campus Bookstore

All textbooks can be purchased at Queen’s Campus Bookstore.

Non-Queen’s Students

All Queen’s Arts and Science Online courses are open to students at other universities. Before applying as a visiting student, request a Letter of Permission from your home university that states that you have permission to take the course and apply it to your degree. See also Apply.

Academic Integrity

Please see Queen’s policy statement on academic integrity for information on how to complete an online course honestly.