Introductory Pharmacology

PHAR 100/3.0

Topics covered include central nervous system stimulants and depressants, narcotics, alcohol, cardiovascular agents, contraceptives, environmental toxicants, mechanism of drug action and disposition, antibiotics, drugs used in sports, over-the-counter drugs, food additives, and vitamins.

Description

This course is designed as an introduction to pharmacology and toxicology. Pharmacology is broadly defined as the effect of drugs and chemicals on living organisms. Toxicology is closely related to pharmacology and is the study of the deleterious effects of drugs and chemicals on living organisms. Pharmacology and toxicology courses are usually taught following courses in physiology and biochemistry. Pharmacology 100/3.0 is designed as a general interest introduction to pharmacology and the knowledge of physiology that is required to understand drug action is included in the textbook and the notes. The course is based on a similar course that has been offered at Queen's for the past 30 years.

Evaluation

Assignment 1 is worth 5% of the final grade
Assignment 2 is worth10% of the final grade
Assignment 3 is worth15% of the final grade
Midterm Exam Online10% of the final grade
The Final Exam is worth60% of the final grade

Final Examination

Students must write their exam on the day and time scheduled by the University. The start time may vary slightly depending on the off-campus exam centre. Do not schedule vacations, appointments, etc., during the exam period.

Final Examination Format

The three-hour final exam will consist of multiple-choice questions of the type given as practice questions at the end of each lesson, and four short-answer questions. The multiple-choice questions will be worth 80%, and the short-answer questions worth 20% of the final exam.

Topics

Section A. History and General Principles of Pharmacology, Lessons 1-5

  • History of Drug Use and Development
  • Drug Advertising, Drug Trials, and Placebo Effects
  • Dose-response Curves and Selective Toxicity
  • Drug Toxicity and Routes of Drug Administration
  • Drug Absorption, Distribution, Metabolism, and Excretion.

Section B. Drugs and the Nervous System, Lessons 1-10

  • Physiological and Pharmacological Aspects of the Central and Peripheral Nervous System
  • Drug Dependence and Drug Abuse
  • Sedative-hypnotics and Anxiolytics
  • Narcotic Analgesics (Opiates, Opioids)
  • Classification of the Major Psychoactive Drugs
  • Classification of Mental Disorders
  • Antipsychotic and Antidepressant Drugs
  • Stimulant Drugs
  • Alcohol (Ethanol)
  • Cannabis
  • Nicotine

Section C. Drugs and the Cardiovascular System, Lessons 1-3

  • Drugs for the Treatment of Angina Pectoris and Congestive Heart Failure
  • Drugs Used for the Treatment and Prevention of Atherosclerosis
  • Antihypertensive Drugs

Section D. Antimicrobial Agents, Lesson 1

  • Antibacterial, Antifungal, Antiviral, and Antimalarial Agents

Section E. Topics of Current Interest in Pharmacology, Lessons 1-6

  • Vitamins
  • Over-the-counter (OTC) Drugs
  • Herbal Remedies
  • Food Additives
  • Drugs in Sports
  • Regulation of Fertility

Section F. Environmental Toxicants and Cancer, Lessons 1-2

  • Chemicals and Cancer
  • Drugs used for the Treatment of Cancer

Instructor

Dr. Racz obtained a Bachelor of Science degree in Pharmacy from the University of Saskatchewan. After three years of practice, he returned to university and obtained a Master’s degree in Medicinal Chemistry and a doctorate in Pharmacology from the University of Alberta. He is currently Professor Emeritus of Pharmacology and Toxicology, School of Medicine, Faculty of Health Sciences, Queen’s University. His interest in educating physicians, nursing science and life science students, and the public in the area of pharmacology and drug use spans almost four decades. His research interests include heavy metal toxicity and drug induced liver injury. He is a past president of the Society of Toxicology of Canada, a consultant to the Committee for The Evaluation of Drugs, Ministry of Health, Ontario and has served on several expert panels.

Dr. Mulder obtained a Bachelor of Science degree in Life Sciences, and Masters and Doctoral degrees in Pharmacology and Toxicology at Queen’s University. Dr. Mulder is currently Adjunct Assistant Professor and Research Associate in the Department of Biomedical and Molecular Sciences at Queen’s University. Her current research interests include environmental toxicants and drug-induced lung and liver toxicities, including cancer. She has been involved with the online version of PHAR100 for over five years and is enthusiastic about teaching pharmacology and toxicology.  

Time Commitment

To complete the readings, assignments, and course activities, students can expect to spend, on average, about 10 - 12 hours per week on the course.

Course Resources

About SOLUS

SOLUS is Queen’s Student On-Line University System. You’ll have access to a SOLUS account once you become a Queen’s student. You’ll use SOLUS to register for courses, add and drop courses, update your contact information, view financial and academic information, and pay your tuition.

About MOODLE

Moodle is Queen's online learning platform. You'll log into Moodle to access your course. All materials related to your course—notes, readings, videos, recordings, discussion forums, assignments, quizzes, groupwork, tutorials, and help—will be on the Moodle site.

About Credit Units

Queen’s courses are weighted in credit units. A typical one-term course is worth 3.0 units, and a typical two-term course is worth 6.0 units. You combine these units to create your degree. A general (three-year) BA requires a total of 90 credit units.

Computer Requirements

To take an online course, you’ll need a good-quality computer (Windows XP/Vista/7, Pentium III, or Mac OS X 10.5, G4 or G5 processor, 256 MB RAM) with a high-speed internet connection, soundcard, speakers, and microphone, and up-to-date versions of free software (Explorer/Firefox, Java, Flash, Adobe Reader). See also Preparing For Your Course.

Dates/Deadlines

The deadlines for new applications to Queen’s are 1 April (for May summer term), 1 June (for July summer term), 1 August (for fall term), and 1 December (for winter term). All documents must be received by the 15th of the month following the deadline. You can register for a course up to one week after the start of the course. See also Dates and Deadlines.

Tuition Fees

Tuition fees vary depending when you start, your year, faculty, and program. Fees for 2014-15 first-year Distance Career Arts & Science Canadian students are as follows: for a 3.0-unit course, $605.31; for a 6.0-unit course, $1210.62. See also Tuition and Payment.

Grading Scheme

The information below is intended for undergraduate students in the Faculty of Arts and Science. Academic Regulations in other Faculties may differ.

Letter Grade Grade Point
A+4.30
A4.00
A-3.70
B+3.30
B3.00
B-2.70
C+2.30
C2.00
C-1.70
D+1.30
D1.00
D-0.70
F0.00

GPA Calculators
Have your SOLUS grade report handy and then follow the link to the Arts and Science GPA calculators.

How does this affect my academics?
See the GPA and Academic Standing page.

Follow the link above for an explanation of how the GPA system affects such things as the Dean’s Honour List, requirements to graduate, and academic progression.

Frequently Asked Questions on the Grading Scheme
Please follow this link to the FAQ's

Campus Bookstore

All textbooks can be purchased at Queen’s Campus Bookstore.

Non-Queen’s Students

All Queen’s Arts and Science Online courses are open to students at other universities. Before applying as a visiting student, request a Letter of Permission from your home university that states that you have permission to take the course and apply it to your degree. See also Apply.

Academic Integrity

Please see Queen’s policy statement on academic integrity for information on how to complete an online course honestly.