Chris Moyes - Professor

Research: We study how the metabolic properties of muscle are governed in relation to evolution, development, and stress, both physiological and environmental: how evolutionary processes influence the diversity in muscle bioenergetics across species and populations, how muscle metabolic genes are regulated in myogenesis, development, physiological remodelling and metabolic pathologies, how animals change muscle bioenergetics in response to environmental stressors, such as temperature and hypoxia.  In all of our studies we attempt to integrate across biological levels of organization, from molecular biology to population biology.

Some Recent Publications:

• Davies, R, Y Wang & CD Moyes. 2011. Intra- and inter-specific variation in metabolic gene expression in relationship to environmental hypoxia. Comparative Biochemistry and Physiology, in press.
• Bremer, K & CD Moyes. 2011. Origins of variation in muscle cytochrome oxidase activity within and between fish species. Journal of Experimental Biology, in press. 
• Duggan, A, KM Kocha, CT Monk, K Bremer & CD Moyes. 2011. Coordination of cytochrome c oxidase gene expression in the remodeling of skeletal muscle. Journal of Experimental Biology in press.
• Seebacher F, MD Brand, PL Else, H Guderley, AJ Hulbert & CD Moyes. 2010. Plasticity of oxidative metabolism in variable climates: molecular mechanisms. Physiological Biochemistry and Zoology 83(5):721-732.
• Little AG, SC Lougheed &CD Moyes. 2010. Evolutionary affinity of billfishes (Xiphiidae and Istiophoridae) and flatfishes (Pleuronectiformes): Independent and trans-subordinal origins of endothermy in teleost fishes. Molecular Phylogenetics and Evolution 56(3):897-904.
• Little AG, KM Kocha, SC Lougheed & CD Moyes. 2010. Evolution of the nuclear-encoded cytochrome oxidase subunits in vertebrates. Physiological Genomics 42(1):76-84.
• Lemoine CM, SC Lougheed & CD Moyes. 2010. Modular evolution of PGC-1alpha in vertebrates. Journal of Molecular Evolution 70(5):492-505.
• Moyes CD & CE Genge. 2010. Scaling of muscle metabolic enzymes: An historical perspective. Comp Biochem Physiol A Mol Integr Physiol 156:344-350.