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Queen's University
 

BIOL 537  2014-15
Dr. W. Snedden

Rm:   3509 Bioscience Complex
Tel:   (613) 533-6154
E-mail:  sneddenw@queensu.ca
Faculty Web Site:  http://www.queensu.ca/biology/people/faculty/snedden.html

RESEARCH AREA/POTENTIAL PROJECTS
Signal Transduction

Research projects can be suited to individual student interests but will encompass the theme of calcium-mediated signal transduction in plants. Plant cells respond to stimuli such as pathogen attack, drought, salinity, and cold stress through signal transduction pathways regulated at some level by the secondary messenger calcium. Cells interpret the information encoded in calcium signals through calcium-binding proteins such as calmodulin. Using the tools of molecular biology, bioinformatics, biochemistry, and cell biology, students will address questions formulated to help unravel some of the signaling events between stimulus perception and cellular response. Depending upon the project selected, students will develop familiarity with methodologies involved in cDNA cloning, PCR, gene expression studies, recombinant protein expression, enzyme assays, protein-protein interaction (yeast two-hybrid screening, interactive cloning), cell and tissue culturing. These projects provide marketable skills in biotechnology and a solid foundation for future lab research. A background in plant biology is an asset, but by no means essential. Students with an interest in laboratory research and some knowledge of molecular biology, biochemistry, and cell biology are encouraged to contact Dr. Snedden to discuss project ideas.

May supervise 1 to 2 students.

STARTING DATE: September (possibly May)

Kingston, Ontario, Canada. K7L 3N6. 613.533.2000