Queen's University : Courses of Instruction in the Faculty of Health Sciences

Not all of the courses listed in the Calendar are offered every year. For the most up-to-date information on the availability of courses offered in the current year, check QCARD or consult with the Life Sciences Office.

MBIO-218*/0.5

Gene Structure and Function (Molecular Biology)

3L;1T alt.wks.

For a complete description, see Biochemistry.

EPID-301*/0.5

Principles of Epidemiology

Basic methods involved in researching the distribution and determinants of health/disease in populations. Core principles of epidemiology are examined, as are the various epidemiological approaches to study design. The latter include descriptive (cross-sectional and ecological), observational (case-control and cohort), and experimental (randomized controlled trials) approaches. PREREQUISITE�� STAT 263* or equivalent, or permission of the Department.

PATH-310*/0.5

Pathology and Molecular Medicine

3L/T

For a complete description, see Pathology and Molecular Medicine.

XRAY-310/0.0

Didactic Training at EOSXT

Required Queen's component for third-year students registered at the Eastern Ontario School of X-Ray Technology. PREREQUISITE Admission to third year of the Collaborative Program in X-Ray Technology.

NSCI-323*/0.5

Cellular Neuroscience

3L;1T

Fundamental properties of the nervous system. Emphasis placed on the properties of neurons that are fundamental to neuron-to-neuron communication, the formation of neural circuits, and the repair of the nervous system following injury. Tutorials introduce techniques and neurological problems that illustrate principles of neural function.

NOTE�� PSYC 271* may not be taken subsequently to NSCI 323*.

PREREQUISITE�� PHGY 210 or PHGY 212 or PHGY 214, or BIOL 338* or PSYC 271*, or permission of the course coordinator.

EXCLUSIONS NSCI 322*, LISC 322*.

NSCI-324*/0.5

Systems Neuroscience

3L;1T

Fundamental properties of the nervous system. Emphasis placed on the properties of neurons and neural circuits that underlie behaviour and cognitive functions within selected neural systems, such as sensory, motor, reward, and autonomic systems. Tutorials introduce techniques and neurological problems that illustrate principles of neural function.
NOTE�� PSYC 271* may not be taken subsequently to NSCI 324*. PREREQUISITE�� PHGY 210 or PHGY 212 or PHGY 214, or BIOL 338* or PSYC 271*, or NSCI 323*, or permission of the course coordinator.��

EXCLUSIONS NSCI 322*, LISC 322*.

LISC-390*/0.5

Integrated Life Sciences Laboratory I

An intermediate laboratory course on the Physiology and Pharmacology of Neuroscience and Gastrointestinal function. Students develop�skills to�acquire and evaluate data and methods. Critical thinking skills are used for the development of arguments, assumptions, and information required to evaluate concepts and hypotheses.
NOTE�� Material Fee: estimated cost $40. PREREQUISITE�� PHGY 214. Priority will be given to BSCH SSP LISC students, or permission of the Department.

COREQUISITE�� PHAR 340*.

LISC-391*/0.5

Integrated Life Sciences Laboratory II

An intermediate laboratory course on the Physiology and Pharmacology of Cardiorespiratory Sciences and Neuroscience. Students develop skills to acquire and evaluate data and methods. Critical thinking skills are used for the development of arguments, assumptions, and information required to evaluate concepts and hypotheses.
NOTE�� Material Fee: estimated cost $40. PREREQUISITES�� PHGY 214, PHAR 340. Priority will be given to BSCH SSP LISC students, or permission of the Department.

EPID-401*/0.5

Biostatistical Data Analysis for Life Science Students

3L;2P

An applied statistics course covering practical topics in tests and confidence intervals for single and multiple samples, ANOVA, linear regression, correlations, methods for categorical data, and nonparametric methods. SPSS package is used in the lab.�The course emphasizes analyzing data arising in life sciences using practical statistical methods. Fall Term. PREREQUISITE�� STAT 263* or equivalent. Restricted to students in honours Life Science programs.

NSCI-401*/0.5

Introduction to Theoretical Neuroscience

2L;1T/S

This course will provide an introduction to the main modelling approaches and theoretical concepts in Neuroscience.�The computational anatomy of the brain and how it implements perception, learning, memory, decision making and motor control, among other topics, will be discussed. PREREQUISITES�� STAT 263* or equivalent and fourth year standing in BSCH LISC degree; or permission of course director. One of NSCI 323*, NSCI 324*, ANAT 312*, PSYC 271*, or equivalent highly recommended.

XRAY-410/0.0

Clinical Training at EOSXT

Required Queen's component for fourth-year students registered at the Eastern Ontario School of X-Ray Technology. PREREQUISITE Admission to fourth year of the Collaborative Program in X-Ray Technology.

LISC-414*/0.5

Progress in Neuroanatomy and Neuropharmacology

A contemporary and comprehensive assessment of the neurochemical anatomy and neuropharmacology of the mammalian and human nervous systems as they relate to development, function and disease. Topics will include dynamics of neurotransmitter interactions, neuronal drug receptor interactions and second messengers, neurotoxicity associated transmitters and neural growth factors. PREREQUISITES�� 70 per cent in PHAR 340* and admission to�fourth year honours BSCH SSP LISC. BMCO students contact the Department.�

LISC-422*/0.5

Cellular and Molecular Neuroscience

1L;2S

An in-depth study of the biophysical properties of neurons and diseases that affect the function of neurons and glia. Topics will include cable properties of dendrites, voltage- and ligand-dependent channels, and molecular mechanisms responsible for neuronal death and regeneration. The course will be based on lectures and student seminars of selected readings. Contact persons: K.Rose (Physiology); C.Barajas-Lopez (Anatomy and Cell Biology). Enrolment is limited. PREREQUISITE�� NSCI 322* (or LISC 322*) or NSCI 323* or NSCI 324* with a minimum of 75 per cent or an equivalent course or permission of the Department.�BMCO students contact the Department.�

LISC-426*/0.5

Current Concepts in Sensorimotor Neuroscience

A multi-disciplinary course exploring advanced concepts of sensorimotor integration from a systems neuroscience perspective. Topics include the neural basis of perception, action selection, reinforcement learning, and motor control. Students will learn to critically evaluate scientific literature and present these concepts to classmates. Restricted to fourth-year students. Enrolment is limited. PREREQUISITES�� NSCI 322* (or LISC 322*) or NSCI 323* or NSCI 324* or equivalent and permission of the Department.

NSCI-429*/0.5

Disorders of the Nervous System

A multi-disciplinary course exploring advanced concepts of clinical neuroscience. Topics include stroke, traumatic brain and cord injuries, neurodegenerative disorders, epilepsy, schizophrenia, depression, deep brain stimulation, pain and placebo effects, normal and abnormal aging, stem cells. Students will learn to critically evaluate scientific literature and present these concepts to classmates during student-led seminars. Restricted to fourth-year students. Enrolment is limited. PREREQUISITE�� One of NSCI 322*, NSCI 323*, NSCI 324*, ANAT 312*, PSYC 271*, or permission of the course coordinators.

CANC-440*/0.5

Cancer Biology and Therapeutics

1L;2T

A consideration of current knowledge and theories about the biology and treatment of cancer.�The course will be presented in a small group format, with active student participation required. PREREQUISITES Admission to fourth year honours in Life Sciences or Biochemistry, with priority to students in the Cancer Research Stream, and permission of the course coordinator.

CRSS-453*/0.5

Principles in Cardiorespiratory Science I

2L;1S

An advanced organ systems approach to the physiological principles underlying cardiac function and oxygen delivery using lectures, seminars, and selected readings. Topics include mechanics and regulation of heart function as well as perturbations in cardiac function. Oxygen delivery and utilization will be examined at the levels of the lung, blood, and tissue. The responses to alterations in oxygen demand and/or supply will also be addressed. Obstructive sleep apnea will be used as a model of a pathological cardiorespiratory system interactions. PREREQUISITES�� PHGY 212 or PHGY 214; admission to honours in BSCH SSP LISC with priority given to students in cardiorespiratory science stream.

LISC-454*/0.5

Cardiovascular Sciences

2L;1S/P

A study of the physiology, pharmacology and anatomy of the cardiovascular system based on lectures, seminars, laboratories and selected readings.�Topics will include structure-function of the heart and blood vessels, mechanisms of signal transduction, cardiovascular pharmacotherapy, the cardiac pump, integrated cardiovascular control, physiology and pharmacology in the control of blood pressure.�Contact person: M.A.Adams (Pharmacology and Toxicology). PREREQUISITES�� ANAT 215* and ANAT 216*, PHGY 212 or PHGY 214, PHAR 340* and BCHM 310 (or BCHM 315* and BCHM 316*). Admission to honours and permission of the Department. Enrolment is limited.

CRSS-456*/0.5

Molecular and Cellular Basis of Cardiovascular Disease

1.5L;1.5S

An intensive course surveying the molecular and cellular mechanisms underlying the pathophysiology of the major cardiovascular diseases, and the current and emerging tolls used in their diagnosis and treatment. Alterations in signalling, metabolism, and structure and function will be discussed to present an integrative view of how cardiovascular diseases develop and progress. PREREQUISITES�� PHGY 212 or PHGY 214; admission to honours in BSCH SSP LISC, with priority to students in the Cardiorespiratory Science Stream.

DDHT-459*/0.5

Principles of Drug Discovery

1L;2T

Advanced study of the early stage components involved in the complex process of drug development including target identification, design and synthesis, structure activity relationships, in vitro and in vivo efficacy determination, biochemical and biological optimization. Fall Term. Contact the Department of Pharmacology and Toxicology for information. PREREQUISITE�� PHAR 340* or equivalent. Priority to students in the Drug Development and Human Toxicology Stream.

DDHT-460*/0.5

Principles of Drug Development

1L;2T

Advanced study of the component parts of the complex process of drug discovery and development and the assessment of human toxicology including drug delivery and formulation, directed toxicology studies, drug disposition, clinical trials, legal issues and regulatory approval. Winter Term. Contact the Department of Pharmacology and Toxicology for information. PREREQUISITES�� DDHT 459*, PHAR 416*. Priority to students in the Drug Development and Human Toxicology Stream.

LISC-488/0.0

Introduction to Animal Care

This WEB CT course is offered each semester and is obligatory for all students undertaking teaching and/or research involving the use of vertebrate animals.� The course covers ethical and legal obligations related to the use of animals. Students take this�course only once. Students are instructed to register through Life Sciences Office for this WEB CT course.
NOTE�� Students are required to complete LISC 488 within 6 weeks of initiating laboratory work. PREREQUISITE� Admission to honours.

NSCI-491*/0.5

Directed Special Laboratory

Laboratory course in a selected area of Neuroscience to be arranged in consultation with individual members of the Centre for Neuroscience Studies. Course involves experimental design, data collection and analysis (approximately 6 hours of laboratory work per week required) as well as a brief communication of the laboratory work. Students are limited to one NSCI 491* research project in�Year�4.
NOTE�� Students whose research project requires the care and/or handling of animals must also register in LISC 488/0.0.
PREREQUISITES Availability of a supervisor and permission of the course coordinator; fourth year honours standing in Life Sciences Neuroscience Stream.

CANC-497*/0.5

Current Topics in Cancer Biology and Genetics

A seminar-based discussion of topics relevant to cancer research. This course will be run as a companion to CANC 499, and will incorporate the practical experience students gain in that course as one foundation of learning. Students will also be introduced to other relevant practical aspects of cancer research, including critical analysis of current literature, and the presentation of scientific results. The course will also involve attending and discussing a number of research seminars offered throughout the year. Enrolment is limited to students concurrently taking CANC 499. Runs throughout the Fall and Winter Terms.

COREQUISITE�� CANC 499.

CRSS-498*/0.5

Cardiorespiratory Rounds

1P;2S

An advanced course in which students attend cardiology and respirology rounds in the Department of Medicine and prepare written and oral reports based on the material presented. The course will provide students with an in-depth exposure to topics in clinical cardiorespiratory science. The course will be offered in alternate years. PREREQUISITES�� PHGY 212 or PHGY 214; admission to honours in BSCH SSP LISC, with priority given to students in the Cardiorespiratory Science Stream.��

CANC-499/1.5

Research Project in Cancer Biology and Genetics

10P

A research project involving the study of cancer biology or genetics. The project will be supervised by a faculty member associated with the Cancer Research Institute, and will provide opportunities for experimental design, data analysis and both written and oral presentation of results. Students must contact a potential faculty supervisor in the Spring preceding registration in fourth year. Enrolment is limited; acceptance by a supervisor required prior to registration.
NOTE�� Students whose research requires the care and/or handling of animals must also register in LISC 488/0.0.
PREREQUISITE Admission to fourth-year honours in BSCH SSP LISC CANC and permission of the course coordinator.

EXCLUSIONS�� ANAT 499, EPID 499, LISC 499, MICR 499, NSCI 499, PATH 499, PHAR 499, PHGY 499. Please note these are all mutual exclusions.

EPID-499/1.5

Research Project in Epidemiology

10P;2T

An examination of an epidemiological research question chosen by the student with guidance from the supervisor. Project will involve review of the literature, development of a proposal, data collection and/or processing, data analysis, a written report and oral presentation. Students will be required to attend and report on seminars of their choosing from a number of venues across campus. Limited enrolment.

NOTE�� Students whose research requires the care and/or handling of animals must also register in LISC 488/0.0.

PREREQUISITES�� EPID 301* or HLTH 323* or permission of the course coordinator; admission to honours in BSCH SSP LISC.��

COREQUISITE�� EPID 401* or permission of the course coordinator.

EXCLUSIONS�� ANAT 499, CANC 499, LISC 499, MICR 455, MICR 499, NSCI 499, PATH 499, PHAR 499, PHGY 499. Please note these are all mutual exclusions.

LISC-499/1.5

Research Project in Life Sciences

10P;2T

An examination of the development and present state of knowledge in selected areas in life sciences and related areas. Research projects involve experimental design, data collection and analysis, written report, and oral presentation. Students will be required to attend seminars and tutorials on topics related to research. Limited enrolment.
NOTE�� Students whose research requires the care and/or handling of animals must also register in LISC 488/0.0. PREREQUISITES Admission to fourth year honours in BSCH SSP LISC and permission of the Department.

EXCLUSIONS�� ANAT 499, CANC 499, EPID 499, MICR 455, MICR 499, NSCI 499, PATH 499, PHAR 499, PHGY 499. Please note these are all mutual exclusions.

NSCI-499/1.5

Research Project in Neuroscience

10P;2T

An investigation into a selected area of neuroscience. The research project involves experimental design, data collection, and analysis, written report and oral presentation. Students will be required to attend seminars and tutorials on topics related to research. Limited enrolment.

NOTE�� Students whose research requires the care and/or handling of animals must also register in LISC 488/0.0.

PREREQUISITES Admission to fourth year honours in BSCH SSP LISC NSCI and permission of the Centre for Neuroscience Studies.

EXCLUSIONS�� ANAT 499, CANC 499, EPID 499, LISC 499, MICR 455, MICR 499, PATH 499, PHAR 499, PHGY 499. Please note these are all mutual exclusions.

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