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Graduate Studies Courses of Instruction Physiology


Physiology
QACS-799 Introduction to Animal Care
This non-credit Moodle course is entirely online and self-directed. It is offered every semester and is obligatory for all students undertaking research, teaching or testing involving the use of vertebrate animals. It should be taken before any animal work is begun. The course will cover ethical and legal obligations related to the use of animals; standards of care; sources of animals; how health and disease affect research data; humane endpoints; principles of anesthesia and recovery surgery. Students need to take this seminar only once. Students who passed LISC-488 are exempt from QACS 799.  Every semester; Moodle; Animal Care Service.
EXCLUSIONS:  LISC-488.
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PHGY-810* Current Concepts in Physiology
An advanced course on current research of selected areas of physiology. This course is comprised of critical lectures and discussion based on recent literature. Compulsory for all new graduate students in Physiology. Winter term; 3 hour seminar.  A.V. Ferguson PREREQUISITE: PHGY-212/812 or equivalent or permission of the course supervisor. Enrolment is limited with priority given to Physiology graduate students.
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PHGY-812 Vertebrate Physiology
An individual reading course for new graduate students with backgrounds in other disciplines. Topics include the function and integrated control of the central and autonomic nervous systems, and the renal, cardiovascular, respiratory, endocrine, and digestive systems. Students will be evaluated by regularly scheduled tests on assigned topics, laboratory reports, and take-home exams. Full course, fall and winter, three 1-hour lectures and one 3-hour laboratory. Faculty.  Not offered 2011-2012. PREREQUISITE: ANAT-311 or equivalent. The student must normally have taken or be taking concurrently BCHM-310 or equivalent.
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PHGY-820* Mammalian Neuroscience
A study of the anatomy and physiology of advanced nervous systems. Additional work will be prescribed for graduate students. Winter term. Not offered 2011-2012. PREREQUISITES: OR COREQUISITES ANAT-311 or 831* or equivalent and PHGY-212/812 or equivalent.
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PHGY-822* Cellular and Molecular Neuroscience
An in-depth study of the biophysical properties of neurons and diseases that affect the function of neurons and glia. Topics will include cable properties of dendrites, voltage- and ligand-dependent channels, and molecular mechanisms responsible for neuronal death and regeneration. The course will be based on lectures and student seminars of selected readings. Given concurrently with LISC-422*, with additional assignments for graduate students. Winter term; one hour didactic lecture/week; 2 hour seminar/week. P.K. Rose.  Not offered 2011-2012.  PREREQUISITE: LISC-322 with a minimum of 70% or an equivalent course or permission of the instructor. Enrollment is limited.
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PHGY-824* Ion Channels of Excitable Cells
The electrophysiology and biophysics of neuronal and cardiac membranes; molecular biology, structure, and function of ion channels.  Students will learn to critically evaluate scientific literature.  Instructional format is primarily student-led seminars.  Winter term; N. Magoski.  Enrolment is limited.  (Offered even years only jointly with PHGY 424). PREREQUISITES: PHGY-212 (or equivalent) with a minimum of 65 percent (or equivalent) or permission of the course supervisor.
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PHGY-825 Medical Neuroscience
A multidisciplinary graduate level course exposing students to the clinical aspects of neuroscience. Didactic lectures cover detailed organization of the nervous system with clinical implications. Laboratories review basic neuroanatomy and pathology. Clinical demonstrations expose students to several neurological disorders. Fall term; didactic lectures, laboratories, and clinical cases (up to 20 hr/week; 9 weeks total). D. Munoz (Physiology), J. Reynolds (Pharmacology), R. Andrew (Anatomy and Cell Biology) NOTE: Classes will begin in late August. PREREQUISITES: Enrolment in graduate faculty and involvement in neuroscience research.
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PHGY-826* Current Concepts in Sensorimotor Integration
A course for graduate students to explore more advanced concepts of sensorimotor integration in the nervous system. This is a multi-disciplinary lecture/seminar course with active student participation expected. The course will consist of weekly sessions focusing on specific concepts such as feature detection, population coding, sensorimotor transformations, reflexes versus voluntary control, central pattern generators. Normally offered concurrently with PSYC-924*.
Winter term; 1 hour lecture; 2 hour seminar/discussion.  M. Dorris.  Offered 2011-2012. 
PREREQUISITE: LISC-322* or equivalent.
EXCLUSION: PSYC-924*.
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PHGY-836* Advanced Physiology
An advanced course for honours and graduate students in which selected areas of physiology are studied in depth. Two hours seminar. N. Magoski and S. Iscoe, Coordinators. PREREQUISITE: Eligibility for admission to this course will be determined by the student's experience in physiology and allied sciences.
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PHGY-840* Advanced Techniques in Digestive Sciences I
A laboratory-based course providing an advanced survey of state-of-the-art methodologies.  This course is designed to give the student experience in cellular, molecular and whole tissue techniques with applications to digestive and related sciences. Fall term; 2 hours seminar / 4 hours laboratory on alternate weeks. R.J. MacLeod.  Not offered 2011-2012.  PREREQUISITE:  Undergraduate degree in biological, biochemical, or life sciences; permission of the course supervisor.  Enrollment is limited.
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PHGY-841* Advanced Techniques in Digestive Sciences II
A laboratory-based course designed to explore in greater depth a sub-group of the techniques studied in PHGY-840* and involving at least two full weeks of intensive laboratory work.  The techniques will be chosen to complement the student's graduate research. Winter or Spring/summer term.  R.J. MacLeod.  Not offered 2011-2012. PREREQUISITE: PHGY-840*. 
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PHGY-844* Gastrointestinal Physiology
The mechanisms and regulation of motor, secretory, digestive and absorptive functions of the gastrointestinal tract are considered.  Students will be required to prepare and present reviews of original literature. Fall/winter terms.  (Enrolment in both terms is required to achieve credit.)  One hour lecture/week; 1 hour seminar alt. wks. M. Blennerhassett.  Offered jointly with PHGY-444. PREREQUISITE:  PHGY-212/812 or equivalent.  Enrolment is limited. 
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PHGY-853* Cellular and Molecular Cardiovascular Sciences
An advanced inter-disciplinary course studying the anatomy, pharmacology and physiology of the cardiovascular system at the molecular and cellular level. The course is comprised of lectures, discussion and student seminars based on recent literature. (Same as ANAT-853* and PHAR-853*). Winter term, 3 hour seminar. C. Ward   PREREQUISITE: Undergraduate degree in Life Science or equivalent or permission from department.
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PHGY-854* Cardiovascular Sciences
A study of the anatomy, pharmacology and physiology of the cardiovascular system based on lectures, seminars, laboratories and selected readings (same as ANAT-854* and PHAR-854*). Topics will include structure-function of the heart and blood vessels, mechanisms of signal transduction, drug effects on second messenger systems, the cardiac pump, integrated cardiovascular control, arterial oxygen transport, control of blood pressure and hypertension. (Offered jointly with LISC-454*.) Additional work will be prescribed for graduate students. Fall term; lectures, seminars and laboratories.  M. Adams.    PREREQUISITES: OR COREQUISITES PHAR-420 and PHGY-212 and -812 or their equivalents. Enrolment limited.
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PHGY-855* Respiratory Physiology
An advanced course examining respiratory mechanics, gas exchange, acid-base balance and the neural control of breathing. Students are required to prepare and present reviews of literature and interpret results of laboratory experiments. Winter term; 2 hours lecture/seminar or 6 hours laboratory. Offered jointly with PHGY-355. J.T. Fisher and S. Iscoe.  PREREQUISITE: A minimum of C (2.0) in PHGY-212 or equivalent.
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PHGY-860* Developmental Neurobiology
Cellular mechanisms operating in development of mammalian nervous system, with invertebrate systems considered when they provide experimental models or illustrate general principles. The capacity and limitations of the adult nervous system to undergo regenerative and plastic changes in structure and function. Winter term; enrolment is limited. Not Offered 2011-2012. PREREQUISITE: PHGY-212/812 with a minimum grade of C (2.0) or PHGY-210 with a minimum grade of B (3.0) or equivalent; permission of the course supervisor
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PHGY-874 Mammalian Neurophysiology
A laboratory-based course to study the properties of mammalian nervous systems and to gain experience with some established neurophysiological techniques. (This course is offered in the fall term jointly with PHGY-474.) Limited enrolment. Full-course, fall term; 2 hours tutorial, 8 hours laboratory. Not offered 2011-2012. PREREQUISITE: PHGY-212/812 or equivalents.
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PHGY-884* Essential Research Skills
Students learn essential research skills such as preparation and critical review of a research proposal, basic theory of physiological instrumentation, histology, and other state-of-art techniques. Fall term. S.D. Iscoe Not offered 2011-2012.
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PHGY-885*/KHS-885* Oxygen Transport in Exercise: Cardiovascular and Respiratory Responses to Increased Muscle Metabolic Demand
A lecture-seminar course examining control mechanisms and limiting factors of the oxygen transport system’s support of exercising muscle metabolism. Topics covered will include the mechanisms involved in regulation of muscle oxygen delivery, conflicting demands of blood pressure vs. muscle oxygen delivery vs. core temperature regulation, limitations to peak aerobic capacity. The impact of training on some of the above topics will also be explored. Fall term. PREREQUISITES: PHGY-210 or equivalent; KINE-429*or equivalent, or permission of instructor.
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PHGY-886*/KHS 886* Exercise Metabolism
A lecture-seminar course in which metabolic, muscular and endocrine adaptations to exercise will be discussed in detail. Particular emphasis will be placed on the effects of acute exercise and physical conditioning on the major energy producing systems (carbohydrate and lipid metabolism). Three hours lectures/seminars.  R. Ross and Staff.  Winter term.  PREREQUISITE: PHGY-210 or equivalent; KINE-427 or equivalent or permission of instructor
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PHGY 888*/KHS-888* Cardiovascular Regulation: Exercise, Extreme Environment and Disease
This course will explore the function and regulation of the cardiovascular system in exercise and extreme environment (eg. altitude, microgravity). Some cardiovascular diseases (eg. hypertension, heart failure) will be examined to understand the implications of dysfunction in cardiovascular regulation. Three hour lecture/seminar; Winter term. M. Tschakovsky.  Not offered 2011-2012.
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PHGY-894* Neuroendocrinology
Students are exposed to an in depth study of selected topics in neuroendocrinology and neuroendocrine techniques. Neuroendocrinology refers to the neural control of endocrine and autonomic function. Areas of focus will include CNS control of cardiovascular function, reproduction, and appetite. In addition, students will learn to critically evaluate scientific literature. Instructional format is primarily student- led seminars. (Offered even years only jointly with PHGY-494).  Winter term. D. Van Vugt. PREREQUISITE: PHGY-212 or equivalent.
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PHGY-895* Endocrinology
A study in depth of selected topics in endocrinology. The emphasis is on student seminars and the conduct of a laboratory project. Fall term; 4 hours laboratory. Not offered 2011-2012. PREREQUISITE: PHGY-212/812 or equivalents.
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PHGY-897* Physiology Seminar Program and Research Project
Students will be required to attend the Departmental seminar program and present a seminar based upon their graduate thesis research. Students will also provide a proposal for their thesis research which includes a review of the related literature. Departmental faculty will evaluate both the seminar and the proposal/review. Enrolment extending over 6 terms (2 years); required for new Master’s level Physiology graduate students.  1 hour seminar/week; Fall, Winter and Summer.  N. Magoski. PREREQUISITE: PHGY-212 or equivalent or permission of the course coordinator.
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PHGY-899 Master's Thesis Research
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PHGY-999 Ph.D. Thesis Research
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Graduate Studies Courses of Instruction Physiology
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