Cahill, C.M., Xue, L., Holdridge, S., Grenier, P., Magnussen, C., Metcalfe, S., LeCourse, S., & Olmstead, M.C. (2013). Changes in morphine reward in a model of neuropathic pain. Behavioural Pharmacology (Epub). http://www.ncbi.nlm.nih.gov/pubmed/23591124

Mahoney, M.K., & Olmstead, M.C. (2013). Neurobiology of an endophenotype: Modelling the progression of alcohol addiction in rodents. Current Opinions in Neurobiology (Epub). http://www.ncbi.nlm.nih.gov/pubmed/23541596

Magrys, S.A., Olmstead, M.C., Wynne-Edwards, K.E., & Balodis, I.S. (2013).  Biochemical responses to alcohol intoxication in healthy males: relationship with impulsivity, drinking behaviour and subjective effects.  Psychophysiology, 50, 204-209. http://www.ncbi.nlm.nih.gov/pubmed/23252809

Shea, A.J, Hewitt, A.M., Olmstead, M.C., Brien, J.F., & Reynolds, J.M. (2012).  Moderate ethanol consumption by the pregnant guinea pig produces neurobeahvioural deficits and increases ethanol preference in offspring.  Behavioural Pharmacology, 23, 105-112. http://www.ncbi.nlm.nih.gov/pubmed/22157142

Hayton, S.J., Maracle, A.C., & Olmstead, M.C. (2012).  Opposite effects of amphetamine on impulsive action with fixed and variable delays to respond.  Neuropsychopharmacology, 37, 651-659. http://www.ncbi.nlm.nih.gov/pubmed/21976042

Hayton, S.J., Mahoney, M.K., Olmstead, M.C. (2012).  Behavioral traits predicting alcohol drinking in outbred rats: An investigation of anxiety, novelty seeking, and cognitive flexibility.  Alcoholism: Clinical and Experimental Research, 36, 594-603.  http://www.ncbi.nlm.nih.gov/pubmed/22004189

Hayton, S.J., Olmstead, M.C., & Dumont, E.C. (2011). Shift in the intrinsic excitability of medial prefrontal cortex neurons following training in impulse control and cued responding tasks. Public Library of Science (PLoS) One, 6, e23885. PubMed Abstract

Tuerke, K.J., Paquette, J.J., Beninger, R.J. & Olmstead, M.C. (2011). Dissociable effects of ultra-low dose naltrexone on tolerance to the antinociceptive and cataleptic effects of morphine. Behavioural Pharmacology, 22, 558-563. PubMed Abstract

Balodis, I.S., Wynne-Edwards, K.E. & Olmstead, M.C. (2011). The stress-response-dampening effect of placebo. Hormones & Behavior, 59, 465-472. PubMed Abstract

Befort, K., Mahoney, M.K., Chow, C., Hayton, S.J., Kieffer, B.L. & Olmstead, M.C. (2011). Effects of delta opioid receptor activation on a response inhibition task in rats. Psychopharmacology, 214, 967-976. PubMed Abstract

Hayton, S.J., Lovett-Barron, M., Dumont, E.C. & Olmstead, M.C. (2010). Target-specific encoding of response inhibition: Increased contribution of AMPA to NMDA receptors at excitatory synapses in the prefrontal cortex. Journal of Neuroscience, 30, 11493-11500. PubMed Abstract

Balodis, I.M., Wynne-Edwards, K.E. & Olmstead, M.C. (2010). The other side of the curve: examining the relationship between pre-stressor physiological responses and stress reactivity. Psychoneuroendocrinology, 35, 1363-1373. PubMed Abstract

Balodis, I.M. Lockwood, K.L. Magrys, S.A. & Olmstead, M.C. (2010). Preference conditioning in healthy individuals correlates with hazardous drinking. Alcoholism: Clinical and Experimental Research, 34, 1006-1012. PubMed Abstract

Balodis, I.M., Potenza, M.N. & Olmstead, M.C. (2010). Recreational drug use and impulsivity in a population of Canadian undergraduate drinkers. Frontiers in Psychiatry, 1, 1-7. PubMed Abstract

Olmstead, M.C., Ouagazzal, A. & Kieffer, B.L. (2009). Mu and delta opioid receptors oppositely regulate motor impulsivity in the signaled nose poke task. Public Library of Science (PLoS) One, 4, e4410. PubMed Abstract

Balodis, I.M., Potenza, M.N. & Olmstead, M.C. (2009). Binge drinking in undergraduates: Binge drinking in undergraduates: Relationships with gender, drinking behaviors, impulsivity and the perceived effects of alcohol. Behavioural Pharmacology, 20, 518-526. PubMed Abstract

Olmstead, M.C., Martin, A., Brien, J.F. & Reynolds, J.N. (2009). Chronic prenatal ethanol exposure increases disinhibition and perseverative responding in the adult guinea pig. Behavioural Pharmacology, 20, 554-557. PubMed Abstract

Paquette, J.J. Wang, H-Y., Bakshi, K. & Olmstead, M.C. (2007). Cannabinoid-induced tolerance is associated with a CB-1 receptor G-protein coupling switch that is prevented by ultra-low dose rimonabant. Behavioural Pharmacology, 18, 767-776. PubMed Abstract

Balodis, I.M., Johnsrude, I.S. & Olmstead, M.C. (2007). Intact preference conditioning in acute intoxication despite deficient declarative knowledge and working memory. Alcoholism: Clinical and Experimental Research, 31, 1800-1810. PubMed Abstract

Pohl, J.L., Olmstead, M.C., Wynne-Edwards, K.E., Harkness, K.L. & Menard, J.L. (2007). Repeated exposure to stress across the peripubertal-juvenile period alters rats’ anxiety- and depression-like behaviors in adulthood: The importance of stressor type and gender. Behavioral Neuroscience, 121, 462-474. PubMed Abstract

Olmstead, M.C. (2006). Animal models of drug addiction: Where do we go from here? Quarterly Journal of Experimental Psychology, 59, 625-53. PubMed Abstract

Olmstead, M.C., Hellemans, H.G.C. & Paine, T.A. (2006). Alcohol-induced impulsivity in rats: An effect of cue salience? Psychopharmacology, 184, 221-228. PubMed Abstract

Balodis, I, MacDonald, T.K. & Olmstead, M.C. (2006). Instructional cues modify performance in the Iowa Gambling Task. Brain and Cognition, 60, 109-17. PubMed Abstract

Olmstead, M.C. & Burns, L.H. (2005). Ultra-low-dose naltrexone suppresses rewarding effects of opiates and aversive effects of opiate withdrawal in rats.Psychopharmacology, 181, 576-581. PubMed Abstract

Hancock, S.D., Menard, J.L. & Olmstead, M.C. (2005). Variations in maternal care influence vulnerability to stress-induced binge eating in female rats.  Physiology and Behavior, 85, 430-439. PubMed Abstract

Wang, H.-Y., Friedman, E., Olmstead, M.C. & Burns, L.H.  (2005). Ultra-low-dose naloxone attenuates chronic morphine-induced changes in Mu opioid receptor – G protein coupling and G bg signalling. Neuroscience, 135, 247-261. PubMed Abstract

Paquette, J.J. & Olmstead, M.C. (2005). Ultra-Low Dose Naltrexone Enhances Cannabinoid-Induced Antinociception. Behavioural Pharmacology, 16, 597-603. PubMed Abstract

Hellemans, K.G.C., Nobrega, J.N. & Olmstead, M.C. (2005). Early environmental experience alters baseline and ethanol-induced cognitive impulsivity: Relationship to forebrain 5-HT 1A receptor binding. Behavioural Brain Research, 159, 207-220. PubMed Abstract

Hayward, M.L., Martin, A.E., Brien, J.F., Dringenberg, H.C., Olmstead, M.C. & Reynolds, J.N. (2004). Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig. Journal of Pharmacology and Experimental Therapeutics, 308, 664-650. PubMed Abstract

Paine, T.A. & Olmstead, M.C. (2004). Impaired response inhibition and conditional discrimination following acute cocaine administration. Psychopharmacology, 175, 443-450. PubMed Abstract

Hellemans, K.G.C., Benge, L.C. & Olmstead, M.C. (2004). Adolescent enrichment partially reverses the social isolation syndrome. Developmental Brain Research, 150, 103-115. PubMed Abstract

Paine, T.A., Dringenberg, H.C. & Olmstead, M.C. (2003). Effectes of chronic cocaine on impulsivity: Relation to cortical serotonin mechanisms. Behavioral Brain Research, 147, 135-147. PubMed Abstract

Dringenberg, H.C. and Olmstead, M.C. (2003). Integrated contributions of basal forebrain and thalamus to neocortical activation elicited by pedunculopontine tegmental stimulation in urethane anesthetized rats. Neuroscience, 119, 839-853. PubMed Abstract

Halpert, A.G., Olmstead, M.C., Beninger, R.J. (2003). Dimenhydrinate produces a conditioned place preference in rats. Pharmacology, Biochemistry and Behavior, 175, 173-179. PubMed Abstract

Ortner, C.N.M., MacDonald, T.K. and Olmstead, M.C. (2003). Alcohol decreases impulsivity in a delay discounting task in humans. Alcohol and Alcoholism, 38, 151-156. PubMed Abstract

Paine, T.A., Jackman, S.L. & Olmstead, M.C. (2002). Psychopharmacology of cocaine-induced anxiety: Role of benzodiazepine, serotonin, and anti-histamine systems. Behavioural Pharmacology, 13(7), 511-523. PubMed Abstract

Hellemans, K.G.C., Shaham, Y., and Olmstead, M.C. (2002). Dissociable effects of acute and prolonged opiate abstinence on drug-seeking and drug-taking. Canadian Journal of Experimental Psychology, 56(4), 241-252. PubMed Abstract

Powell, K.J., Abul-Husn, N.S., Jhamandas, A., Olmstead, M.C., Beninger, R.J. and Jhamandas, K. (2002). Paradoxical effects of the opioid antagonist naltrexone on morphine analgesia, tolerance and reward. Journal of Pharmacology and Experimental Therapeutics, 300(2), 588-96. PubMed Abstract

Halpert, A.G., Olmstead, M.C., & Beninger, R.J. (2002). Mechanisms and abuse liability of dimenhydrinate. Neuroscience and Biobehavioral Reviews, 26(1), 61-67. PubMed Abstract

Inglis, W.L., Olmstead, M.C., and Robbins, T.W. (2001). Selective deficits in attentional performance on the 5-choice serial reaction time task following pedunculopontine tegmental nucleus lesions. Behavioral Brain Research, 123, 117-131. PubMed Abstract

Olmstead, M.C., Lafond, M. Everitt, B.J. and Dickinson, A. (2001). Cocaine-seeking by rats is a goal-directed action. Behavioral Neuroscience, 115, 394-402. PubMed Abstract

Johnston, L.D., Beninger, R.J. and Olmstead, M.C. (2001). Pimozide, like extinction, devalues stimuli associated with sucrose-taking. Pharmacology, Biochemistry and Behavior, 68, 583-590. PubMed Abstract

Olmstead, M.C., Parkinson, J.A., Miles, F.J., Everitt, B.J. and Dickinson, A. (2000). Cocaine-seeking by rats: Regulation, Reinforcement and Activation. Psychopharmacology, 152, 123-131. PubMed Abstract

Inglis, W.L.,Olmstead, M.C., and Robbins, T.W. (2000). Pedunculopontine tegmental nucleus lesions impair stimulus-reward learning in autoshaping and conditioned reinforcement paradigms. Behavioral Neuroscience, 114, 285-294. PubMed Abstract

Everitt, B.J., Parkinson, J.A., Olmstead, M.C., Arroyo, M., Robledo, P. and Robbins, T.W. (1999). Associative processes in addiction and reward: the role of amygdala-ventral striatal subsystems. Annals of the New York Academy of Sciences, 877, 412-438. PubMed Abstract

Parkinson, J.A., Olmstead, M.C., Burns, L.H., Robbins, T.W. and Everitt, B.J. (1999). Dissociation in effects of the nucleus accumbens core and shell on appetitive Pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by d-amphetamine. Journal of Neuroscience, 19, 2401-2411. PubMed Abstract | Free article from J. Neurosci

Olmstead, M.C., Inglis, W.L., Bordeaux, C.P, Clarke, E.J., Wallum, N.P., Everitt, B.J. and Robbins, T.W. (1999). Lesions of the pedunculopontine tegmental nucleus do not affect sucrose consumption, choice or contrast effects. Behavioral Neuroscience, 113, 732-743. PubMed Abstract

Olmstead, M.C., Munn E.M., Franklin K.B. and Wise R.A. (1998). Effects of pedunculopontine tegmental nucleus lesions on responding for intravenous heroin under different schedules of reinforcement. Journal of Neuroscience, 18, 5035-5044. PubMed Abstract | Free article from J. Neurosci

Olmstead M.C., Robbins T.W. and Everitt B.J. (1998). Basal forebrain cholinergic lesions enhance conditioned approach responses to stimuli predictive of food. Behavioral Neuroscience, 112, 611-629. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1997). The development of a conditioned place preference to morphine: effects of microinjections into various CNS sites. Behavioral Neuroscience, 111, 1324-1334. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1997). The development of a conditioned place preference to morphine: effects of lesions of various CNS sites. Behavioral Neuroscience, 111, 1313-1323. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1996). Differential effects of ventral striatal lesions on the conditioned place preference induced by morphine or amphetamine. Neuroscience, 71, 701-708. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1994). Lesions of the pedunculopontine tegmental nucleus abolish catalepsy and locomotor depression induced by morphine. Brain Research, 662, 134-140. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1994). Lesions of the pedunculopontine tegmental nucleus block drug-induced reinforcement but not amphetamine-induced locomotion. Brain Research, 638, 29-35. PubMed Abstract

Olmstead, M.C. and Franklin K.B. (1993). Effects of pedunculopontine tegmental nucleus lesions on morphine-induced conditioned place preference and analgesia in the formalin test. Neuroscience, 57, 411-8.PubMed Abstract

Kofman O., McGlynn S.M., Olmstead M.C. and Yeomans J.S. (1990). Differential effects of atropine, procaine and dopamine in the rat ventral tegmentum on lateral hypothalamic rewarding brain stimulation. Behavioral Brain Research, 38, 55-68. PubMed Abstract

 

Book Chapters

Hancock, S.D., & Olmstead, M.C. (2010). Animal models of eating disorders. In: Olmstead, M.C. (Ed.).  Animal Models of Drug Addiction Totowa NJ: Humana Press Inc.

Balodis, I.M. & Olmstead, M.C. (2009). Laboratory measures of risk-taking: Relevance to pathological gambling. In: Columbus, F.E. (Ed.). The Psychology of Gambling. Hauppauge HY: Nova Science Publishers.

Hayton, S.J. & Olmstead, M.C. (2009). Fractionating animal models of motor impulsivity: Reconciling the neurochemistry of disinhibition. In: Granon, S. (Ed.) Endophenotypes of psychiatric and neurodegenerative disorders in animal models. Kerala India: Transworld Research Network.

Burns, L.H., Leri, F. & Olmstead, M.C.  (2006). Ultra-low-dose naltrexone reduces dependence and addictive properties of opioids. In: Dean, R., Bilsky, E., Negus, S. & Wickens J. (Eds.). Opioid Receptors and Antagonists: From Bench to Clinic. Volume in Contemporary Neuroscience Series. 

Beninger, R.J. and Olmstead, M.C. (1999). The role of dopamine in the control of locomotor activity and reward-related incentive learning. In: Miller, R. & Wickens, J. (Eds.) Brain Dynamics and the Striatal Complex. Chur, Switzerland: Harwood Academic Publishers.

If you would like reprints of any of these articles, please email my research assistant, Megan Mahoney: 6mm75 at queensu.ca