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Queen's University
 
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Current Studies

    Neurocognitive Enhancement in a Vocational Services Program

    This treatment research project is aimed at examining the utility of neurocognitive enhancement for individuals with mental disorders who are preparing to return to work. It is being conducted in collaboration with the Vocational Services team at the Frontenac Community Mental Health Centre.

      STEPS: Structured Therapy to Enhance Purposeful Speech

      This treatment project is being led by Katherine Holshausen in the CPD Lab. She is using an operant conditioning paradigm to increase the goal-directedness of speech of by inpatients with schizophrenia.


      Relevant Publications:
      http://www.ncbi.nlm.nih.gov/pubmed/23510635
      http://www.ncbi.nlm.nih.gov/pubmed/21561739
      http://www.ncbi.nlm.nih.gov/pubmed/18571378
      http://www.ncbi.nlm.nih.gov/pubmed/15800156


      Beyond Stigma

       Several of our studies are focused on applying more rigorous experimental design and objective assessment of biobehavioural responses to the characteristics of severe mental illness in order to better understand what constitutes stigma and what are predictable responses to atypical behaviours. To date, we have used EEG, behavioural coding, and covert assessments of threat perception.

      Relevant Publications:
      http://www.ncbi.nlm.nih.gov/pubmed/21944429
      Best M & Bowie CR. Neurophysiological responses to schizophrenia-associated communication abnormalities. Schizophrenia Research, In Press
       

        Speech Perception and Communication in Individuals with Auditory Hallucinations

        In this study, a collaboration with Dr. Kevin Munhall in the Psychology Department at Queen's University, we are measuring receptive and productive speech mechanisms differences as a function of auditory hallucination status.

        Relevant Publications:

        Chronic Psychiatric Disorders: Linking Genes to Functional Disability

         This study, led by Ann Pulver, ScD, at John’s Hopkins University and funded by the National Institute of Mental Health, examines the genetic correlates of cognitive and functional deficits in schizophrenia and bipolar disorder.

        Relevant Publications:
        http://www.ncbi.nlm.nih.gov/pubmed/21843926
        http://www.ncbi.nlm.nih.gov/pubmed/21562142
        http://www.ncbi.nlm.nih.gov/pubmed/20478878


          Remote Cognitive Remediation

           We and other clinician scientists have demonstrated the efficacy and effectiveness of cognitive remediation for improving neurocognition and everyday functioning for those with chronic mental illnesses. Unfortunately, this treatment is not widely available or covered by most health care plans.  We are trying to change that.  We have a series of studies where we are using internet-based drills and practice along with asynchronous therapist communication through blogs and online videos.

          Relevant Publications:
          http://www.ncbi.nlm.nih.gov/pubmed/23343011
          http://www.ncbi.nlm.nih.gov/pubmed/22929873
          http://www.ncbi.nlm.nih.gov/pubmed/22581070

          Kingston, Ontario, Canada. K7L 3N6. 613.533.2000