Department of Psychology

Queen's University
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Christopher Bowie

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Associate Professor

M.A., Hofstra University,1997
Ph.D., Hofstra University, 2002

Lab Site | Curriculum Vitae (PDF, 332 KB)

T: 613.533.3347

219 Craine Hall
Psychology Department
Queen's University
Kingston, ON K7L 3N6

Research Interests

Neurocognition in Psychosis
Functional Outcomes in Psychotic Disorders
Novel Behavioral Assessment Methods
Early Intervention and Prevention of Severe Mental Illness
Pharmacological and Behavioral Treatment of Cognitive Deficits

Selected Publications

Publications from last three years:
(Note: Supervised students in italics)

Best MW, Gupta M, Bowie CR*, Harvey PD. A Longitudinal Examination of the Moderating Effects of Symptoms on the Relationship between Functional Competence and Real World Functional Performance in Schizophrenia. Schizophrenia Research, In Press. *Corresponding Author

Chengappa KNR, Bowie CR, Schlicht PJ, Fleet D, Brar JS, Jindal R. Randomized placebo-controlled adjunctive study of an extract of Withania somnifera for cognitive dysfunction in bipolar disorder.J Clin Psychiatry, 2013, 74:11

Depp CA, Strassnig M, Mausbach BT, Bowie CR, Wolyniec P, Thornquist MH, Luke JR, McGrath JA, Pulver AE, Patterson TL, Harvey PD. Association of obesity and treated hypertension and diabetes with cognitive ability in bipolar disorder and schizophrenia. Bipolar Disorders, In Press.

Ho J, Moore R, Cardenas V, Bowie CR, Patterson TL, Mausbach, BT. Direct and mediated effects of cognitive function with multidimensional outcome measures in schizophrenia: the role of functional capacity. Journal of Clinical and Experimental Neuropsychology, In Press.

Porter RJ, Bowie CR, Jordan J, Malhi G. Cognitive remediation as a treatment for major depression – a rationale, review of evidence, and recommendations for future research. Australia and New Zealand Journal of Psychiatry, In Press.

Holshausen K, Bowie CR, Mausbach BT, Patterson TL, Harvey PD. Neurocognition, functional capacity, and functional outcomes: The cost of inexperience. Schizophrenia Research, In Press.

Bowie CR, Grossman M, Gupta M, Oyewumi LK, Harvey PD. Cognitive remediation in schizophrenia: efficacy and effectiveness in patients with early versus long-term course of illness. Early Intervention in Psychiatry, In Press.

Harvey PD & Bowie CR. Improving cognition in schizophrenia. Minerva Psichiatrica, In Press.

Lepage M, Bodnar M, Bowie CR. Neurocognition in relation to clinical and functional outcome in schizophrenia. Canadian Journal of Psychiatry, In Press.

Iftene F, Bowie CR, Milev R, Hawken E, Talikowska-Szymczak E, Potopsingh D, Hanna S, Mulroy J, Groll D, Millson R.  Identification of primary polydipsia in a severe and persistent mental illness outpatient population: A prospective observational study. Psychiatry Research, In Press.

Best MW, Fitzpatrick M, Milev R, Bowie CR, Jokic R. Utility of the Berlin Questionnaire for Predicting Obstructive Sleep Apnea in Individuals with Treatment-Resistant Depression. Sleep and Breathing, In Press.

Gupta M, Holshausen K, Best M, Jokic R, Milev R, Bernard T, Gou L, Bowie CR. Relationships among neurocognition, symptoms, functioning in treatment-resistant depression. Archives of Clinical Neuropsychology, 2013, 28, 272-281.

McClure MM, Harvey PD, Bowie CR, Iacoviello B, Siever LJ. Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder. Schizophrenia Research, 2013, 144, 146-150.

Bowie CR, Gupta M, Holshausen K, Jokic R, Best, M, Milev, R. Cognitive remediation for treatment resistant depression: Effects on cognition and functioning and the role of online homework. Journal of Nervous and Mental Disorders, 2013, 201, 680-685.

Holshausen K, Harvey PD, Elvevag B, Foltz PW, Bowie CR. Semantic coherence predicts formal thought disorder and adaptive behavior in older inpatients with schizophrenia. Cortex, In Press.

Bowie CR, Gupta M, Holshausen K. Cognitive remediation therapy for mood disorders: rationale, early evidence, and future directions. Canadian Journal of Psychiatry, 2013, 58, 319-325.

Mausbach BT, Moore RC, Davine T, Cardenas V, Bowie CR, Ho J, Jeste DV, Patterson TL. The use of the theory of planned behavior to predict engagement in functional behaviors in schizophrenia. Psychiatric Research, 2013, 205, 36-42.

Cardenas V, Abel S, Bowie CR, Tiznado D, Depp CA, Patterson TL, Jeste DL, Mausbach BT. When functional capacity and real world functioning converge: the role of self-efficacy. Schizophrenia Bulletin, 2013, 39, 908-916.

Best M & Bowie CR. Neurophysiological responses to schizophrenia-associated communication abnormalities. Schizophrenia Research, 2013, 148, 157-162.

Chengappa KNR, Turkin SR, DeSanti S, Bowie CR, Brar JS, Schlicht PJ, Murphy SL, Hetrick ML, Bilder R, Fleet D. A preliminary, randomized, double-blind, placebo-controlled trial of L-Carnosine to improve cognition in schizophrenia. Schizophrenia Research, 2012, 142, 145-152.

Harvey PD, Bowie CR. Cognitive enhancement in schizophrenia: Pharmacological and cognitive remediation approaches. Psychiatric Clinics of North America, 2012, 35.

Bowie CR, McGurk SM, Mausbach BT, Patterson TL, Harvey PD. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real world behavior. American Journal of Psychiatry, 2012, 169, 710-718.

Gupta M, Holshausen K, Mausbach B, Patterson T, Bowie CR. Predictors of change in functional competence and real world behavior following Functional Adaptation Skills Training for schizophrenia. Journal of Mental and Nervous Disease, 2012, 200, 705-711.

Gould F, Bowie CR, Harvey PD. The influence of demographic factors on functional capacity and everyday functional outcomes in schizophrenia. Journal of Clinical and Experimental Neuropsychology, 2012, 34, 467-475.

Depp CA, Mausbach BT, Bowie C, Wolyniec P, Thornquist MH, Luke JR, McGrath JA, Pulver AE, Harvey PD, Patterson TL. Determinants of occupational and residential functioning in bipolar disorder. Journal of Affective Disorders, 2012, 136, 812-818.

Depp CA, Mausbach BT, Harmell AL, Salva GN, Bowie CR, Harvey PD, Patterson TL. Meta-analysis of the association between cognitive abilities and everyday functioning in bipolar disorder. Bipolar Disorders, 2012, 14, 217-226.

Mausbach BT, Roepke SK, Chattillion EA, Harmell AL, Moore R, Romero-Moreno R, Bowie CR, Grant I. Multiple mediators of the relations between caregiving stress and depressive symptoms. Aging and Mental Health, 2012, 16, 27-38.

Harvey PD, Bowie CR. Cognitive Remediation in Severe Mental Illness. Innovations in Clinical Neuroscience, 2012, 9, 1-4.

Bowie CR, Mclaughlin D, Carrión RE, Auther AM, Cornblatt BA. Cognitive changes following antidepressant or antipsychotic treatment in adolescents at clinical risk for psychosis. Schizophrenia Research, 2012, 137, 110-117.

Lowenstein DA, Czaja SJ, Bowie CR, Harvey PD. Age-associated differences in cognitive performance in older patients with schizophrenia: a comparison with healthy older adults. American Journal of Geriatric Psychiatry, 2012, 20, 29-20

Gupta M, Bassett E, Iftene F, Bowie CR. Functional outcomes in schizophrenia: understanding the competence-performance discrepancy. Journal of Psychiatric Research, 2012, 46, 205-211.

Harvey PD, McClure MM, Patterson TL, McGrath JA, Pulver A, Bowie CR, Siever LJ. Impairment in functional capacity as an endophenotype candidate in severe mental illness. Schizophrenia Bulletin, 2012, 16, 27-38.

Mausbach BT, Depp CA, Bowie CR, Harvey PD, McGrath JA, Thornquist MH, Luke JR, Wolyniec PS, Pulver AE, Patterson TL. Sensitivity and specificity of the UCSD Performance-Based Skills Assessment (UPSA-B) for identifying functional milestones in schizophrenia. Schizophrenia Research, 2011, 132, 165-170.

Bowie CR, Gupta M, Holshausen K. Disconnected and underproductive speech in schizophrenia: Unique relationships across multiple indicators of social functioning. Schizophrenia Research, 2011, 131, 152-156

Larochette AC, Harrison AG, Rosenblum Y, Bowie CR. Additive neurocognitive deficits in adults with ADHD and depressive symptoms. Archives of Clinical Neuropsychology, 2011, 26, 385-395

Adelsky MB, Bowie CR, Goldberg TE, Serper MR. Adaptive competence impairment and cognitive deficits in acutely ill schizophrenia patients residing in nursing homes. American Journal of Geriatric Psychiatry, 2011, 19, 752-756

Depp CA, Mausbach BT, Harvey PD, Bowie CR, Wolyniec PS, Thornquist MH, Luke JR, McGrath JA, Pulver AE, Patterson TL. Social Competence and observer-rated social functioning in bipolar disorder.  Bipolar Disorders, 2010, 12, 843-850

Leifker FR, Patterson TL, Bowie CR, Mausbach BT, Harvey PD. Psychometric Properties of Performance-based Measurements of Functional Capacity: Test-Retest Reliability, Practice Effects, and Potential Sensitivity to Change. Schizophrenia Research, 2010, 119, 246-252

Bowie CR, Depp C, McGrath JA, Wolyniec P, Mausbach BT, Thornquist MH, Luke J, Patterson TL, Harvey PD, Pulver AE. Prediction of Real World Functional Disability in Chronic Mental Disorders: A Comparison of Schizophrenia and Bipolar Disorder. American Journal of Psychiatry, 2010, 167, 1116-1124 

Mausbach BT, Harvey PD, Pulver AE, Depp CA, Wolyniec PS, Thornquist JR, McGrath JA, Bowie CR, Patterson TL. Relationship of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to multiple indicators of functioning in people with schizophrenia and bipolar disorder.  Bipolar Disorders, 2010, 12, 45-55

Harvey PD, Reichenberg A, Bowie CR, Patterson TL, Heaton RK. The course of neuropsychological performance and functional capacity in older patients with schizophrenia: influences of previous history of long-term institutional stay. Biological Psychiatry, 2010, 67, 933-939