This is an archived copy of the 2021-2022 calendar. To access the most recent version of the calendar, please visit https://queensu-ca-public.courseleaf.com.
Program Notes
Subject Code for Anatomy: ANAT
Subject Code for Biochemistry: BCHM
Subject Code for Cancer Research: CANC
Subject Code for Cardiorespiratory Science: CRSS
Subject Code for Drug Discovery and Human Toxicology: DDHT
Subject Code for Life Sciences: LISC
Subject Code for Microbiology and Immunology: MICR
Subject Code for Neuroscience: NSCI
Subject Code for Pathology and Molecular Medicine: PATH
Subject Code for Pharmacology and Toxicology: PHAR
Subject Code for Physiology: PHGY
Subject Code for Public Health Sciences: EPID
Subject Code for Reproduction and Development: REPD
Associate Dean, Life Sciences and Biochemistry: Louise Winn
Office: Botterell Hall, Room 815
World Wide Web Address: www.healthsci.queensu.ca/liscbchm/
Telephone: 613-533-6527
Email Address: lifesci@queensu.ca
Overview
The hallmark of the Life Sciences program is a unique blend of disciplines represented by basic and clinical biomedical science departments in the Faculty of Health Sciences. These departments include Biomedical and Molecular Sciences, Public Health Sciences, and Pathology and Molecular Medicine, in collaboration with the Cancer Research Institute, the Centre for Neuroscience Studies, the Cardiac, Circulation and Respiratory Group, and the Research Group in Reproduction and Development.
The subjects that fall under the umbrella of the Life Sciences program include traditional biomedical disciplines devoted to the anatomical, biochemical, epidemiological, immunological, microbiological, pathological, pharmacological, and physiological sciences. In addition, there are Sub-plans dedicated to contemporary trans-disciplinary themes in the cardiovascular and respiratory sciences, drug development and human toxicology, cancer biology and genetics, and neuroscience.
The Department of Biomedical and Molecular Sciences is responsible for Biochemistry Plans (General/Minor (Science), Major, Specialization) and plays a primary role in the Life Sciences Plans (General/Minor (Science), Major, Specialization). The Department is a unique amalgam of scientists and teachers who share a common goal: to ameliorate the consequences of disease and trauma by training the next generation of health care scientists and professionals. To meet this goal, the Department draws on the depth and breadth of the scientific expertise of its members. Contemporary courses are offered in the anatomical, biochemical, microbiological, immunological, pharmacological, and physiological sciences and in a wide range of cross-disciplinary studies (e.g. cardiovascular and respiratory sciences, drug development, cancer biology and genetics, and neuroscience). These courses are integral to the various Biochemistry and Life Sciences Plans.
Program Policies
Laboratory Safety
Departmental Safety Rules are strictly enforced. A standard white laboratory coat is required for all laboratory courses. Shoes must be closed at both heel and toe. Additional safety requirements will be described at the first laboratory in each laboratory-based course.
Access to Third and Fourth Year Courses
Students in the Life Sciences Specialization Plan (LISC-P-BSH) will be given priority enrolment to those courses that are required to meet third- and fourth-year core and option requirements. Students in both the Life Sciences Specialization and the Life Sciences Major Plans (LISC-P-BSH and LISC-M-BSH) should further note that a minimum cumulative GPA of 2.50 is a required prerequisite to access those fourth-year courses to complete these Plans. See Academic Regulations 2.4 and 2.6.
Advice to Students
Students should seek academic counseling from staff in the Associate Dean’s office:
Course Prefix | Counsellor | Contact Information |
---|---|---|
BCHM and LISC | Louise Winn | lifesci@queensu.ca |
BCHM and LISC | Katherine Rudder | lifesci@queensu.ca |
BCHM and LISC | Candice Phillips | biochem@queensu.ca |
Students may also seek academic counseling from one of the counselors listed below.
Course Prefix | Counsellor | Contact Information |
---|---|---|
ANAT | Leslie MacKenzie | mackenzl@queensu.ca |
BCHM | Robert L. Campbell | robert.campbell@queensu.ca |
CANC and PATH | Christopher Nicol | nicolc@queensu.ca |
CRSS and PHGY | Shetuan Zhang | shetuan.zhang@queensu.ca |
EPID | Ana Johnson | ana.johnson@queensu.ca |
DDHT and PHAR | Nikki A. Philbrook | nikki.philbrook@queensu.ca |
MICR | R. Keith Poole | poolek@queensu.ca |
NSCI | Jason Gallivan | gallivan@queensu.ca |
- The Biomedical Discovery Sub-plan is recommended to students who wish to gain advanced laboratory experience or experiential learning in Anatomy or Epidemiology/Public Health or Immunology or Microbiology or Pathology or Pharmacology or Physiology, or Reproduction and Development.
- The Biomedical Sciences Sub-plan provides more flexibility in choice of options and electives than other sub-plans, and is recommended to students who wish to obtain a wide-ranging foundation in the life sciences with opportunities for advanced study in selected topics.
The remaining four sub-plans are devoted to contemporary trans-disciplinary streams and place a high premium on laboratory-based research and seminar-based learning.
- The Cancer Sub-plan is recommended to students who wish to proceed to graduate studies and research in Cancer Biology and Genetics. Students intending to take this sub-plan should consult the list of option courses required for completion of the program, and consider appropriate courses in Year 3.
- The Cardiorespiratory Sub-plan is recommended to students who wish to proceed to graduate studies and research in the cardiovascular and respiratory sciences. Students intending to take this sub-plan should complete PHGY 355 Biomedical Respiratory Physiology/3.0 in Year 3.
- The Drug Discovery and Human Toxicology Sub-plan is recommended to students who are interested in enriched study in the fields of drug discovery and development as well as in mechanisms of drug and toxicant action. Students will gain advanced knowledge which will make them competitive for graduate studies and marketable in particular employment areas (e.g. government regulatory agencies and pharmaceutical companies).
- The Neuroscience Sub-plan is recommended to students who wish to proceed to graduate studies and research in the neurosciences. Students intending to take this option should complete either NSCI 323 Cellular Neuroscience/3.0 or NSCI 324 Systems Neuroscience/3.0 in Year 3. It is strongly recommended that students in this sub-plan complete both courses.
Life Sciences Major Plan is recommended to students who wish to pursue a wider range of study than is possible with the Life Sciences Specialization Plan. Access to specialized courses at the 400 level may be limited, with priority given to students in the Life Sciences Specialization Plan program.
Preparation for a Teaching Career
Students wishing to enter teaching as a career are advised to consult the Faculty of Education concerning the prerequisites for the B.Ed. program options.
Note Students enrolled in this program will be required to work with animals and tissues obtained from animals.
Faculty
Sheela Abraham, Michael A. Adams, John Allingham, R. David Andrew, Bruce W. Banfield, Sam Basta, Gunnar Blohm, Chantelle Capicciotti, Che Colpitts, Graham P. Côté, Andrew Craig, Peter L. Davies, Qingling Duan, Eric C. Dumont, Kimberly Dunham-Snary, Ronald A. Easteal, Alastair V. Ferguson, Jason Gallivan, Katrina Gee, Nader Ghasemlou, Charles H. Graham, Zongchao Jia, Glenville Jones, Frederick W.K. Kan, Michael D. Kawaja, Madhuri Koti, Alan Lomax, Leslie W. MacKenzie, Neil S. Magoski, Nancy L. Martin, Donald H. Maurice, Christopher R. Mueller, Douglas P. Munoz, Mark Ormiston, Terence Ozolins, Stephen C. Pang, Martin Paré, P. Martin Petkovich, R. Keith Poole, James N. Reynolds, Stephen H. Scott, Amber Simpson, Steven P. Smith, Patrick Stroman, Myron R. Szewczuk, Chandrakant Tayade, Christopher A. Ward, Louise M. Winn, Shetuan Zhang
Programs
- Environmental Life Science – Specialization (Science) – Bachelor of Science (Honours)
- Life Sciences – Specialization (Science) – Bachelor of Science (Honours)
- Life Sciences – Major (Science) – Bachelor of Science (Honours)
- Life Sciences – General (Science) – Bachelor of Science
- Life Sciences – Minor (Science)
Courses
This anatomy course is designed to introduce students to the basic structure and functional relationship of the human body. Through a series of weekly learning modules, students will learn about the basic language of Gross Anatomy and Histology in order to understand the working of various body systems. This course is also suitable for individuals who have a general interest in human anatomy.
A basic anatomy course with an emphasis on clinical relevance of structure and function of human body systems.
RECOMMENDATION 4U Biology.
The general principles of human structure and function as appreciated through a survey of the morphological sciences, including: history of anatomy; embryology; neuroanatomy; developmental, microscopic and gross anatomy of the locomotor system.
NOTE Priority will be given to students registered in a LISC Specialization Plan.
The general principles of human structure and function as appreciated through a survey of the development, microscopic and gross anatomy of the body systems: cardiovascular, respiratory, immune/lymphatic, endocrine, digestive and genitourinary.
NOTE Priority will be given to students registered in a LISC Specialization Plan.
This course is designed to introduce the foundations of human structure and function to students at all levels of post-secondary education. Through a series of learning modules, students will develop an understanding of the architecture of the human body through interactive study using a virtual cadaver. This course will survey the gross and microscopic anatomy of the body organ systems including the skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic/immune, respiratory, digestive, urinary and reproductive systems.
NOTE Only offered online. Consult the Bachelor of Health Sciences program office.
NOTE May not be taken for credit towards the Plan requirements of the LISC Specialization or Major Plans.
LEARNING HOURS 120 (60O;60P)
Introduction to mammalian histology, or microscopic anatomy, a branch of anatomical sciences focusing on structures and functions of tissues and cells at the light and electron microscope level. Structure-function relationships within many tissues and organs at the cell and tissue level will be a focus.
NOTE Priority will be given to students registered in a LISC Specialization Plan or Health Sciences plan.
LEARNING HOURS 120 (36L;24Lb;60P)
Study of the structure and function of the nervous system by lectures, hands-on laboratories, brain dissection, and readings. Topics include, but are not limited to, sensory and motor systems, brain imaging, and clinical examples.
Gross and functional anatomy of the back, body wall, upper and lower limbs, including blood supply and neural controls.
Gross and functional anatomy of the thorax, abdomen and pelvis, head and neck.
ANAT 380 will explore regional anatomy of the human body focusing on the major organ systems, their components, and the relationships between them. In this course, students will apply anatomical knowledge to collaboratively solve case-based clinical scenarios, and develop a realistic clinical case based on an underlying anatomical issue.
Note: Also offered online.
LEARNING HOURS may vary 120(48O;72P)
A focused histological and cell biological study of three selected mammalian tissues, organs and/or systems.
Comprehensive overview of cellular and molecular mechanisms that direct embryogenesis including gastrulation, neurulation, establishment of body axes, differentiation, sex determination, limb development, organogenesis, and teratology. Participation in seminar presentations and group discussions is required.
LEARNING HOURS 114 (24L;12S;1I;77P)
In ANAT 471, students work individually/collaboratively to explore stages of normal human embryonic and fetal development and how changes in underlying mechanisms link to common congenital or developmental abnormalities. Various assessments include quizzes, a journal club, a PBL investigating a developmental abnormality, a midterm and final exam.
LEARNING HOURS 120 (48O;72P).
An examination of the development and present state of knowledge in selected research areas of Anatomy and Cell Biology. Research project involves experimental design, data collection and analysis, written report, poster presentation and oral presentation. Students will be required to attend seminars and tutorials on topics related to research. Limited enrolment; restricted to fourth year honours, permission of the department required.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
This seminar course will cover current topics in male and female reproduction and pregnancy. The format includes critiques of original publications and attendance of and reports on the interdepartmental reproductive seminar series. Credit value: 0.5, spread over Fall and Winter terms (every second year). Attendance and reporting of interdepartmental reproductive group seminars:12 h Overview lectures by professors on assigned topics:12 h Presentation and participation in student seminars:12 h Minimal quota of students for course to run:4 Course Coordinators: Various Graduate Faculty but overseen by a designated Faculty. Not offered 2010-2011.
A detailed study of the gross and functional anatomy of the human body with emphasis on clinical application. The course is given jointly with part of Phase I of the medical curriculum. Additional work prescribed for graduate students. Full course; lectures, laboratories and tutorials. C.W.Reifel and Staff. Learning Materials: $40
A contemporary and comprehensive assessment of the neurochemical features of the mammalian nervous system as they relate to development, function and disease. Winter term; 3 hour lecture/seminar. Offered alternate years. M.D. Kawaja. Offered 2010-2011.
An in-depth study of the biophysical properties of neurons and diseases that affect the function of neurons and glia. Topics will include cable properties of dendrites, voltage- and ligand-dependent channels, and molecular mechanisms responsible for neuronal death and regeneration. The course will be based on lectures and student seminars of selected readings. Given concurrently with LISC-422*, with additional assignments for graduate students.
A multidisciplinary graduate level course exposing students to the clinical aspects of neuroscience. Didactic lectures cover detailed organization of the nervous system with clinical implications. Laboratories review basic neuroanatomy and pathology. Clinical demonstrations expose students to several neurological disorders. Fall; didactic lectures, laboratories, and clinical cases (up to 20 hr/week; 9 weeks total) M.D. Kawaja (Anatomy and Cell Biology), D. Munoz (Physiology), J. Reynolds (Pharmacology and Toxicology)
A course for graduate students to explore more advanced concepts of sensorimotor integration in the nervous system. This is a multi-disciplinary lecture/seminar course with active student participation expected. The course will consist of weekly sessions focusing on specific concepts such as feature detection, population coding, sensorimotor transformations, reflexes versus voluntary control, central pattern generators. Normally offered concurrently with PSYC-924*. Winter term; 1 hour lecture; 2 hour seminar/discussion. S. Scott
Detailed histological assessment of selected organs and tissues. Winter Term, alternating years. Lectures and seminars. M.D. Kawaja. Not offered 2010-2011.
A series of lectures and workshops illustrating modern teaching philosophy and technique specifically designed for teaching Anatomy in the Health Sciences.Fall Term. Drs. R.A. Easteal and L.W. MacKenzie.
Microteaching as a technique for new and experienced teachers will involve the presentation of a series of 3-minute micro lectures with video recording and feed back sessions.Winter Term. Drs. R. A. Easteal and L. W. MacKenzie.
This half-credit course will be offered to students who have completed ANAT-417* in their undergraduate studies in the Queen's Life Sciences Program. Through a series of tutorials and seminars, the course will focus on the most up-to-date discoveries in three areas of developmental biology. The areas reflect the expertise in the department. Winter Term. Dr C.W. Reifel.
This half-credit course will be offered to students who have completed ANAT-312* in their undergraduate studies in the Queen's Life Sciences Program. Through a series of tutorials and seminars, the course will focus on the most up-to-date discoveries in three areas of neuroanatomy. The areas reflect the expertise in the department. Fall Term. R.D. Andrew
An advanced mammalian histology course including advanced staining techniques in demonstrating various components of Histological sections.Winter Term. Drs. L.W. MacKenzie and S.C. Pang.
The course has two components. A 7 week (26 hour) series of discussions on assigned readings, selected readings and a 45 minute presentation by each student on medical and ethical aspects of obstetrics, gynaecology, endocrinology, population and gender health and psychology. The second component is a 50 hour Human Placenta Research Summer Workshop. Summer Term. Dr. B.A. Croy
This course is designed to equip graduate students with modern research techniques in Cell and Molecular Biology. This intense 2-week course consists of 2-3 hours of lecture and 6-8 hours hands-on laboratory exercise per day. Techniques include light microscopy and immunohistochemistry, electron microscopy and immunocytochemistry, RNA, DNA and protein isolation, Northern and Western blot analysis, probe design, and conventional and realtime PCR. Summer Term in odd years. Dr. M.Y. Tse and Dr. S.C. Pang
An investigation into concepts and techniques in selected areas of research offered in the Department of Anatomy. Research projects carried out under the supervision of a staff member. Winter term. S.C. Pang, Staff
The topics will be chosen on the basis of special needs of the students, and must be approved by the Coordinator of Graduate Studies. Fall or winter; seminars.
Chemical principles as applied to biochemistry, human and clinical biochemistry.
NOTE Primarily intended for students in Nursing. Arts and Science students require permission of the Department.
LEARNING HOURS 118 (24L;16T;6G;36O;36P)
RECOMMENDATION 4U Chemistry.
Molecules and macromolecules that participate in the replication and expression of genes. Current methods for exploring the structure, function, and manipulation of genetic material.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
LEARNING HOURS may vary. 120 (36L;12T;72P)
EQUIVALENCY MBIO 218/3.0.
This course will introduce general biochemical concepts that will allow for an understanding of the biological and chemical principles underlying human physiology, health and disease. The course will provide self-paced learning and utilize evidence-based teaching principles, small group learning, peer-learning and guided-independent learning methodologies to provide an inclusive learning environment. Students will gain an enhanced appreciation of general applications of biochemistry as applied in day to day healthy life and during the disease states, diagnosis and clinical management of metabolic disorders.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
NOTE This introductory biochemistry online course is intended for prospective students in Nursing, Environmental Sciences, Engineering, Commerce, and general science programs.
NOTE May not be taken for credit towards the Plan requirements of the BCHM or LISC Specialization or Major Plans.
LEARNING HOURS may vary 126 (66O;60P)
Principles of protein biochemistry, enzymology, and protein engineering. Metabolism of carbohydrates, amino acids and lipids. Role of coenzymes. Generation and storage of metabolic energy. Principles of regulatory mechanisms, membrane structure and function, hormone action, and cellular signalling.
NOTE Students lacking the prerequisites CHEM 222/3.0 or CHEM 282/3.0 may take these courses as a corequisite with permission of the Department.
LEARNING HOURS 348 (72L;36Lb;240P)
This course will provide an in depth view of the molecular mechanisms controlling how genes are organized, regulated and expressed in mammalian cells. Once you understand how proteins are made, you will learn a variety of approaches to visualize and measure proteins and enzymatic activities in mammalian cells.
NOTE If you have taken or are currently registered in BCHM 310/9.0 you may contact the department for permission to enroll.
LEARNING HOURS 120 (36L;84P)
Principles of protein biochemistry, enzymology, and protein engineering.
NOTE Students lacking the prerequisites CHEM 222 or CHEM 282 may take these courses as a corequisite with permission of the Department.
LEARNING HOURS 120 (36L;12O;72P).
Metabolism of carbohydrates, amino acids and lipids. Role of coenzymes. Generation and storage of metabolic energy. Principles of regulatory mechanisms, membrane structure and function, hormone action, and cellular signalling.
LEARNING HOURS 122 (36L;8O;78P)
Application of separation and assay techniques to the study of proteins, metabolism and molecular biology. Attendance required in both terms. Enrollment will be limited because of laboratory constraints, and selection will be based on academic standing.
LEARNING HOURS 360 (96Lb;264P)
Application of separation and essay techniques to the study of proteins, metabolism and molecular biology.
NOTE This course is for outgoing Biochemistry Honours exchange students who are not able to obtain the equivalent of BCHM 317/6.0 when on exchange.
LEARNING HOURS 180 (48Lb;132P)
An introduction to the field of applied genomics for identifying genes underlying multi-factorial traits, diseases, and drug treatment outcomes. Basic principles of gene mapping studies will be covered in the context of recent advances in the field including statistical methods, and integrative analyses of biological datasets.
Notes: Also offered online
LEARNING HOURS may vary: 120(48O;72P)
This course presents an integrated approach to the study of protein function. Topics include proteomic techniques, mass spectrometry, protein purification, imaging, surface plasmon resonance, calorimetry, bioinformatics and protein evolution, protein modifications and processing, interpretation and applications of 3-D structure, and structure-function relationships.
NOTE Offered jointly with BMED 810/3.0. Students in a LISC or BMCO Plan should contact the Department regarding prerequisites and permission to register.
This course concentrates on the molecular biology of mammalian models particularly mechanisms involved in human diseases. The human genome project, forensic analysis, DNA diagnostics of human diseases, models of transcriptional and growth regulation and cancer, DNA repair, RNA processing and translation are all discussed. Emphasis on recent findings and course materials will be drawn from current reviews.
NOTE Offered jointly with BMED 811/3.0. Students in a LISC or BMCO Plan should contact the Department regarding prerequisites and permission to register.
LEARNING HOURS 120 (36L;84P)
Biochemical research techniques with emphasis on nucleic acids, protein structure and function, regulation of gene expression and metabolic control processes.
NOTE 6.0-unit course offered in the Fall Term.
An independent research project by each student in one of the departmental research labs. Evaluation is based on oral presentation, lab performance and a thesis.
NOTE 6.0-unit course offered in the Fall Term.
Principles of regulatory mechanisms; regulation of cellular function and growth by oncogenes, growth factors, isoprenoids and steroid hormones. Receptors, second messengers and protein phosphorylation. Correlation of cell ultrastructure with biochemical function. Description of the components, assembly, metabolism and evolution of cellular structures are described.
NOTE Offered jointly with BMED 832/3.0. Students in a LISC Plan should contact the Department regarding prerequisites and permission to register.
LEARNING HOURS 120 (30L;6G;84P)
Tutorials, assignments and demonstrations in important subjects in biochemistry emphasizing topics of broad interest. Particular emphasis will be paid to the applications of biochemical knowledge and new technologies.
NOTE Students in the BCHM Specialization Plan registered in BCHM 421 and BCHM 422 will not be allowed to register in BCHM 441; Students in the LISC Specialization Plan registered in one of ANAT 499, CANC 499, EPID 499, LISC 499, MICR 455, MICR 499, NSCI 499, PATH 499, PHAR 499or PHGY 499 will not be allowed to register in BCHM 441.
LEARNING HOURS 120 (21L;9S;3G;3Oc;84P).
Seminars, assignments and demonstrations focused on important subjects in biochemistry, emphasizing the scientific pipeline, from discovery to commercialization. Particular emphasis will be placed on applications of biochemical knowledge and new technologies.
NOTE Students in the BCHM Major Plan registered in BCHM 441/3.0 will not be allowed to register in BCHM 442/3.0.
LEARNING HOURS 120 (18S;18G;84P)
This course will focus on the principles of proteomics and metabolomics and their application in the new systems biology `omics approach to scientific discovery. This course will emphasize both the methodologies used in proteomics and metabolomics, as well as their applications in both research, medical diagnostics, and disease management.
NOTE: Only offered online. Consult the Bachelor of Health Sciences program office.
LEARNING HOURS may vary: 114 (36O;78P)
Discussions and presentations on current topics in molecular biology. The emphasis will be on mammalian systems and will cover a wide range of topics relating to recent advances in molecular biology. Typical topics include gene regulation, replication, DNA repair, forensic analysis, human genomics and genetics. Marks are based on student presentations and essays typically in "News and Views" or Mini-Review formats. Three hours per week, presentations and discussions of original papers. Fall; C. Mueller.
Lectures and discussions on mechanisms of metabolic control. Recent research on a wide range of specific metabolic systems is examined critically. Emphasis is placed on biochemical factors and principles which play a role in the integration and control of metabolism. Lectures and seminars, three hours per week; Winter; Alternate years.
This course consists of weekly presentations and discussions of recent advances towards the understanding of protein structure and function. Topics of discussion include novel approaches, techniques and concepts in the discovery of protein functions. Students will develop skills in literature research, critical evaluation of published work, effective presentation and discussion of papers.A specific theme, such as cell motility, may be used to illustrate research approaches employed to study biological systems in general. Three lecture hours per week; Winter; Alternate years;A. Mak.
This course is intended to provide the student with the opportunity to gain familiarity with their research field. Students will review the literature related to their proposed graduate research thesis project and write a series of essays on topics selected in consultation with their supervisor; these will be evaluated by a supervisory committee consisting of their supervisor and two other faculty members. They will also develop a written draft research proposal that will be presented to their supervisory committee and defended in a final oral examination. This course is not mandatory but is highly recommended to be taken by students in the first full term of the graduate program. G.P. Côté (course coordinator).
This course will focus on protein structure and function with special emphasis on membrane proteins and selected soluble protein systems. The course will consist of lectures and presentations that will be organized around specific readings from the recent literature. A portion of the course will be devoted to membrane protein structure and function. Selected examples of structural and functional studies of soluble proteins will include enzymes and inhibitors; protein-protein interactions; protein engineering; high-throughput identification of enzyme substrates. Some instruction will be given in homology modeling and database analysis of gene products. Three hours per week, half course lectures and seminars.
All courses are half-courses which are offered either in the fall or winter term if there is sufficient student interest. Detailed outlines of course content are available during the summer of each year. Most courses are offered in alternate years.
This online course is designed to introduce students to cancer as an evolutionary problem. The material is unique in that it emphasizes the impact of the immune system in fighting cancer while at the same time shaping tumour cell evolution. Students will need to synthesize the impact of factors present in the tumour microenvironment.
NOTE Also offered online.
LEARNING HOURS may vary 120 (72O;48P)
A consideration of current knowledge and theories about the biology and treatment of cancer. The course will be presented in a small group format, with active student participation required.
NOTE Priority to students in the LISC Specialization Plan, CANC Sub-Plan.
A seminar-based discussion of topics relevant to cancer research. This course will be run as a companion to CANC 499/12.0, and will incorporate the practical experience students gain in that course as one foundation of learning. Students will also be introduced to other relevant practical aspects of cancer research, including critical analysis of current literature, and the presentation of scientific results. The course will also involve attending and discussing a number of research seminars offered throughout the year.
LEARNING HOURS 120 (36S;12G;72P)
A research project involving the study of cancer biology or genetics. The project will be supervised by a faculty member associated with the Cancer Research Institute, and will provide opportunities for experimental design, data analysis and both written and oral presentation of results. Students must contact a potential faculty supervisor in the Spring preceding registration in fourth year. Enrolment is limited; acceptance by a supervisor required prior to registration.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
An advanced organ systems approach to the physiological principles underlying cardiac function and oxygen delivery using lectures, seminars, and selected readings. Topics include mechanics and regulation of heart function as well as perturbations in cardiac function. Oxygen delivery and utilization will be examined at the levels of the lung, blood, and tissue. The responses to alterations in oxygen demand and/or supply will also be addressed. Obstructive sleep apnea will be used as a model of a pathological cardiorespiratory system interactions.
NOTE Priority given to students in the CRSS Sub-Plan.
A study of the physiology, pharmacology and anatomy of the cardiovascular system. Topics include integrative mechanisms of control and pharmacotherapy involved in short-term and long-term control of the circulation in health and disease.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
LEARNING HOURS may vary: 138 (18L;10S;10G;100P)
An intensive course surveying the molecular and cellular mechanisms underlying the pathophysiology of the major cardiovascular diseases, and the current and emerging tolls used in their diagnosis and treatment. Alterations in signalling, metabolism, and structure and function will be discussed to present an integrative view of how cardiovascular diseases develop and progress.
NOTE Priority given to students in the CRSS Sub-Plan.
An advanced course in which students attend cardiology and respirology rounds in the Department of Medicine and prepare written and oral reports based on the material presented. The course will provide students with an in-depth exposure to topics in clinical cardiorespiratory science. The course will be offered in alternate years.
NOTE Priority given to students in the CRSS Sub-Plan.
Advanced study of the early stage components involved in the complex process of drug development including target identification, design and synthesis, structure activity relationships, in vitro and in vivo efficacy determination, biochemical and biological optimization.
NOTE Priority given to students in the LISC Specialization Plan, DDHT Sub-Plan.
LEARNING HOURS 120 (12L;24G;84P)
RECOMMENDATION PHAR 416/3.0.
Advanced study of the component parts of the complex process of drug discovery and development and the assessment of human toxicology including drug delivery and formulation, directed toxicology studies, drug disposition, clinical trials, legal issues and regulatory approval.
NOTE Priority given to students in the LISC Specialization Plan, DDHT Sub-Plan.
LEARNING HOURS 120 (36L;84P)
RECOMMENDATION DDHT 459/3.0 and PHAR 416/3.0.
Basic methods involved in researching the distribution and determinants of health/disease in populations. Core principles of epidemiology are examined, as are the various epidemiological approaches to study design. The latter include descriptive (cross-sectional and ecological), observational (case-control and cohort), and experimental (randomized controlled trials) approaches.
An applied statistics course covering practical topics in tests and confidence intervals for single and multiple samples, ANOVA, linear regression, correlations, methods for categorical data, and nonparametric methods. The lab uses statistical software. The course emphasizes analyzing data arising in life sciences using practical statistical methods.
An examination of an epidemiological research question chosen by the student with guidance from the supervisor. Project will involve review of the literature, development of a proposal, data collection and/or processing, data analysis, a written report and oral presentation. Students will be required to attend and report on seminars of their choosing from a number of venues across campus. Limited enrolment.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
This course provides foundational knowledge on how human evidence relevant to public health is created, assessed, and used, with a focus on epidemiologic methods. Topics include measures of health status; risk factors and associations with health outcomes; study design including descriptive, analytical, and intervention approaches; validity issues; critical appraisal; assessment of causation; ethics; and application of epidemiologic evidence in public health decisions.
This course provides an overview of theoretical and conceptual foundations of public health. It examines the social determinants of health and population health approaches to promote and protect health. It instils in students an understanding of the historical achievements, core values and ethical frameworks that guide public health action.
The aim of this introductory course is to describe how health services are organized and delivered in Canada. Students who take the course will: 1) understand the inputs, delivery and outputs of the Canadian health system; 2) recognize and explain the factors that influence change in this system; and 3) consider current health policy issues in Canada.
This course deals with advanced methods and issues in the design, conduct, analysis and interpretation of epidemiologic studies. The content focuses on observational study design and analysis, and builds on epidemiologic principles presented in EPID-801. Data analysis will emphasize the application and interpretation of statistical concepts in epidemiologic research. Three term-hours, winter; every year. W. King.
The course teaches students to apply theories of leadership and change to the analysis and development of public health actions. Approaches to leading change are reviewed at a variety of levels - self, team, organization, individuals, community, government. Practical examples are drawn from the core programmatic and functional areas of public health practice and exemplify the role of the local heath unit organization in leading change.
This course provides an overview of social research methods and tools to assist students to complete the "evidence to action" program planning and evaluation cycle. Topics covered include: defining the issue, using surveillance data, engaging the community, conducting a stakeholder analysis, survey methods, handling qualitative data, building logic models, choosing indicators, communicating the results, taking action.
This course is designed to allow students to become
familiar with different types of economic evaluations in healthcare and when to employ particular types of economic evaluation. Topic covered will include: cost-effectiveness, cost-utility, cost-benefit, budget impact analyses, and policy decision-making. No prior
economics background is required. Three term hours.
This course will cover material relevant to the design and conduct of controlled clinical trials. Design topics will include methods used to achieve unbiased results with improved precision, such as adequate sample size, randomization, blinding, pre- and post-stratification, cross-over designs, placebos and the counting of relevant events. Attention will be given to the problems of conducting multi-centre clinical trials. Topics covered will include drafting of protocols, design of data forms, logistics of data flow, methods of follow-up, data management and quality control, periodic reporting, final data analysis and the production of final reports. Ethical issues and the role of randomized trials in clinical investigation will be discussed. Three term-hours, winter. R. Meyer, D. Tu
This course is intended for graduate students, clinical fellows and postdoctoral fellows who are engaged or interested in cancer research. The course will focus on concepts and methodological issues central to the conduct of epidemiologic studies of cancer etiology and control. Topics will include: an introduction to basic epidemiologic concepts; biologic and clinical concepts central to the investigation of cancer; study design; clinical epidemiology; molecular epidemiology; and cancer control and prevention. Three term-hours; winter; every year. B.MacKillop.
This course will demonstrate the way in which epidemiological principles guide the practice of medicine and the design of clinical research. Topics will include how to select the correct design for a study that addresses a clinical question,how to evaluate the quality of clinical publications and research proposals, and how to prepare a clinical research proposal. Three term hours,Fall every year. W. Mackillop.
This course provides an overview of basic statistical concepts, principles, and techniques essential for public health and epidemiologic research. This course covers both descriptive and inferential statistics. Topics covered include measures of association, t-tests, regression, chi-square tests, analysis of variance, and some nonparametric methods. Emphasis is on understanding and interpreting fundamental statistical analyses from health research.
This course deals with the commonly used regression methods proven useful in health services research and the epidemiologic analysis of the relationship between traits, exposures or treatments, and diseases or other medical outcomes. The course emphasizes the statistical modeling approach with topics including multiple regression, analysis of variance and covariance, reliability of measurements, analysis of categorical data, logistic regression, Poisson regression and survival analysis. This course includes a compulsory SAS Programming component. PREREQUISITE: EPID-821* (or permission of instructor for Biostatistics students).
An advanced course in the theoretical issues and analytical practices in epidemiology, and biostatistics. Topics may vary but major topics include analysis of longitudinal and survival data using various regression models; Techniques and strategies for regression modeling; Novel analytic approaches in epidemiology; multivariate analysis methods including discriminant analysis, principal components and factor analysis. PREREQUISITE: EPID- 821* + knowledge of basic statistical modeling techniques deemed adequate by the Instructors.
This half term course (involving 39 hours of instruction) is required for students enrolled in the Masters of Public Health Program in the Department of Community Health and Epidemiology in the second year of their program. This course examines the determinants of health from a population health perspective including social, cultural, and economic factors; physical environmental factors; personal health practices; individual coping skills; and health services. Three term hours, fall; every year. B. Alvarado-Llano.
This course provides an introduction to public health leadership and administration. The intent is to familiarize with the main components of the organization, financing, and delivery of public health services in Canada. Students will also learn principles of strategic planning, public health marketing, the legal and ethical basis for public health interventions, and systems thinking for resolving community health and organizational problems.Finally, the course will build competencies in critical thinking and communication skills necessary for public health practice. Three term hours; Winter. Duncan Hunter.
This course provides a foundation in infectious disease epidemiology. Principles and methods related to infectious disease biology, outbreak detection and investigation, and the methodological, analytical, and diagnostic tools are covered. Specific infectious diseases that pose contemporary challenges in public health and/or have national or global public health impact are discussed. Three term hours.
PREREQUISITE: EPID-801 or permission of the instructor.
This course will provide an overview of the epidemiology of some of the leading non-infectious causes of morbidity and mortality in Canada and will highlight the key methodological considerations for the study of each disease or health problem.
PREREQUISITES: EPID-801* & EPID-821* or equivalents with permission of course coordinator
This course will provide students with in-depth substantive knowledge about the evolution of health issues that have shaped policy and mental health services.
PREREQUISITES: EPID-801* or permission of course instructor
This course provides students with a foundation for understanding, assessing and mediating environmental exposures. Methods for assessing and communicating about exposures, risks and standards in air, water, soil and food are introduced. Case studies of managing hazardous exposures are reviewed. Environmental health policy implications of global climate, energy use and disaster planning are explored. PREREQUISITE: EPID-801, EPID-821 or equivalent, or permission of instructor.
This course provides foundational instruction in qualitative research methodology for students in the public health sciences, including theoretical basis, study design, research ethics, sampling and recruitment, data collection, data analysis, and disseminating research findings. Topical areas may include ethnography, grounded theory, phenomenology, participatory research, and other areas.
This course introduces health services research methods as they are applied to routinely collected health data. It covers methodologic approaches for assessing healthcare effectiveness, quality, and access. The course also provides an introduction to the Ontario ICES data holdings and the conduct of health services research using those data.
This course assists students to lay the foundation for continuing professional development in public health practice. Students are introduced to the personal learning portfolio and coached to chart their progress in developing skills and competencies through a combination of workshops, seminars, and on line learning modules.
The 400¿hour practicum placement provides MPH students with an opportunity to work in the public health field and contribute to evidence-informed public health practice. Through the practicum students demonstrate and enhance the knowledge, skills and attitudes they have learned from course work as well as reflect on and advance their career development. Placement activities and roles will vary according to the needs and interests of both host organization and the student. This course is graded on a
PASS/FALL basis.
PREREQUISITES: EPID 801, EPID 802, EPID 803, EPID 806, EPID 821 and EPID 886 (16-month students only), or approval from the Practicum Coordinator.
Under the guidance of the supervisor, students will carry out a practicum project in a health research group/site and practise biostatistical methods and data analysis, or conduct methodology research in a biostatistical project. Students will summarize the results of the project in a written report that will be reviewed and orally defended.
This course provides in-depth integration of advanced concepts in epidemiology, with theory and examples, including causation and causal inference, study design and conduct, alternate designs, confounding, effect modification, internal and external validity, misclassification, source populations, statistical power and sample size, epidemiologic data analysis and interpretation, meta-analysis and selected specific research areas. This is an advanced course intended primarily for Ph.D. students. Sessions consist of lectures, seminars, student presentations and discussions. Three term- hours, fall and winter. Patti Groome and Harriet Richardson
This course provides a conceptual and historic view of the Public Health Sciences, as well as a look at contemporary issues in Public Health research ethics, research methodology and knowledge translation. Guided each year by student interests and advanced training needs, the course delves into specific substantive public health research areas including for example: chronic disease, environmental health, infectious disease, injury and disability, maternal and child health, occupational health, humanitarian contexts, Indigenous health and/or health services research.
This course will use an evidence-based approach to address the impact of social and environmental exposures and circumstances on health at both an individual and population level.
Multidisciplinary course organized around five major fields of scientific endeavour: anatomy, physiology, pathology, pharmacology, and population and global health
Introduction to fundamentals of health-related research methods with a focus on developing critical reasoning skills. Using examples from a wide range of health-related research topics, students will gain familiarity and skills to assess primary literature at a basic level.
Emphasis will be placed on population health, instead of the health of individuals. Population and Global health prioritize partnerships and resource sharing, instead of unilateral relationships, and focuses on advocacy.
Teams of students will identify the critical questions that must be answered to resolve major controversies or gaps of knowledge that impede the application of fundamental principles in the Life Sciences to health care. The end product will be a written report and public presentation that is accessible to a wide audience.
NOTE Restricted to students registered in Level 3 or above in a (LISC Specialization or Major Plan or BCHM Specialization or Major Plan or BIOL Plan or PSYC Plan).
NOTE Limited enrollment available to BIOL and PSYC students.
LEARNING HOURS 126 (6L;6S;33G;33O;48P)
Introduction to ethical, legal and regulatory requirements for people working in the health professions.
Students will develop an understanding of the three primary types of research employed in health sciences: Experimental quantitative, observational quantitative, and qualitative
Examines technologies that are in use/evolving in the aging support and anti-aging arsenal, including gerontechnology and anti-aging technologies.
Students will learn a number of different laboratory techniques, developing skills in scientific methodology, data acquisition, and interpretation. Students will also attain skills in critical thinking and hypothesis development, as well as gain experience in writing a laboratory report, and participating in research presentations.
NOTE Priority will be given to students registered in a LISC Specialization Plan.
An intermediate laboratory course on the Physiology and Pharmacology of Cardiorespiratory Sciences and Neuroscience. Students develop skills to acquire and evaluate data and methods. Critical thinking skills are used for the development of arguments, assumptions, and information required to evaluate concepts and hypotheses.
NOTE Priority will be given to students registered in a LISC Specialization Plan.
LEARNING HOURS 108 (36Lb;36O;36P)
A multi-disciplinary course exploring advanced concepts of sensorimotor integration from a systems neuroscience perspective. Topics include the neural basis of perception, action selection, reinforcement learning, and motor control. Students will learn to critically evaluate scientific literature and present these concepts to classmates.
Students will take knowledge gained from GLPH 271/3.0 or LISC 271/3.0, and apply it in this course, which will focus on more advanced topics of population and global health, as well as provide experiential learning.
This course examines basic principles of infectious diseases, including epidemiology, pathophysiology, transmission, and control of infectious agents, with an emphasis on antimicrobial therapy and resistance.
This course will strengthen students¿ abilities to respond to a community¿s health needs through a practical service learning position with an approved local or international community health organization
This course provides the student with a foundation in the subdisciplines of bacteriology, virology, parasitology, and immunology. The course is designed to examine common infectious diseases through a body-systems approach. Laboratory and tutorial sessions emphasize diagnostic microbiology.
A general course providing insight into the role immunology plays in health and disease. Social and political issues associated with the increasing importance of this field will be discussed. Topics will include vaccines, immune system stimulators, organ transplants, allergies, cancer, AIDS, rheumatoid arthritis and diabetes. Offered in Spring Term only.
NOTE The course has been designed primarily for students in the humanities, social sciences and non-biological sciences. No previous training in science is required.
A fundamental study of the structure and growth of microorganisms and viruses. The roles of microbes in aquatic, terrestrial and human environments will be considered.
LEARNING HOURS 120 (36L;18Lb;66P)
This course focuses on 1) the overall organization of the immune system, 2) the role of the immune system in combating diseases caused by common pathogens as well as adverse reactions of the immune system and 3) application of the basic knowledge of immunology to the field of infectious disease prevention and control by vaccines and treatment of cancer. The unique features of this course lie in its overall structure and delivery that will prepare the student for further in-depth learning in the field of immunology.
NOTE This online course in infection and immunity is designed for students from various biological sciences and allied health backgrounds at all levels of post-secondary education and is recommended as a foundation course for students pursuing a life sciences career.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
NOTE May not be taken for credit towards the Plan requirements of the LISC Specialization or Major Plans.
LEARNING HOURS may vary 114 (36O;78P)
An introduction to the biology of microbes, including both pathogenic & beneficial bacteria, viruses, fungi, & protozoa. This overview of the biological features of these microorganisms will highlight these organisms¿ roles in the environment & in human health contributing to infectious diseases vs. maintaining healthy microbiomes.
NOTE Only offered online. Consult the Bachelor of Health Sciences Program office.
LEARNING HOURS 120 (60O;60P)
This immersive laboratory course is designed to give students the opportunity to apply important microbiological and biochemical research techniques to the study of antibiotic resistance. Students work in small groups on a semester-long project, developing valuable lab skills that will support them with future research
opportunities.
LEARNING HOURS 120(36Lb;48O;36P)
This course will focus on the roles of microbes in health (human microbiome) and disease (pathogens). The molecular mechanisms of bacterial/viral virulence and the host response will be examined in order to develop an in depth understanding of the etiology of infectious diseases and the benefits derived from the human microbiome. Consult the Bachelor of Health Sciences program office
NOTE Also offered online. Learning Hours may vary.
The general principles and mechanism of immune reaction. Immunochemical and immunobiological aspects of antibody formation and cell-mediated immunity in health and disease will be considered.
LEARNING HOURS 144 (36L;36O;72P)
Integrates the key principles of immunology to facilitate learning of immunology as it relates to human health and disease. This course offers real-life case studies, problems encountered and solutions applied, immunology virtual laboratory simulation, and extensive coverage of the basic science underlying each topic in the module.
Also offered online.
LEARNING HOURS may vary:120(48O;72P)
An emphasis on the wide variety of bacteria and their habitats focusing on their physiology, metabolism, genetics and their influence on the environment. The laboratory component will feature enrichments for selected groups of microorganisms and analysis of isolates by light microscopy, gas and high pressure liquid chromatography etc. (0/54/0/0/0)~ COURSE DELETED IN 2008/09 ~
An in-depth analysis of the genetics, biochemistry, assembly and function of the major structures of the procaryotic cell. Emphasis on the experimental approaches in the current literature.
A detailed description of the processes of heredity in bacteria including a discussion of gene structure and evolution, gene expression and its control, the exchange of genetic material in the microbial world and genetic engineering and its applications. The laboratory component will emphasize modern approaches to genetic engineering.
NOTE Offered in alternate years to MICR 435/3.0.
Further study of contemporary virology, using the textbook as a guide to particles, genomes, replication, expression, infection and pathogenesis. Emphasizing reading and writing to develop skills in observation and critical thinking, important attributes in understanding the scientific method.
NOTE Offered in alternate years to MICR 451/3.0.
The nature of selected animal virus groups and their interactions with the host in disease production. Special emphasis on the pathogenesis of tumour and human immunodeficiency viruses.
NOTE Offered in alternate years to MICR 450/3.0.
LEARNING HOURS 120 (24L;12T;84P)
Course material will focus on the molecular basis for virus pathogenesis including host immune responses to virus infection, and viral countermeasures. Emphasis will be on viral infections that result in gastrointestinal, haematological, neurological, and respiratory diseases. Tutorials will focus on discussion of current and seminal literature.
In-depth analysis of experimental approaches for the study of insect viruses in cell culture and practical hands-on laboratory experience through a research project.
Advanced immunology course focused on current topics in immunology and immunology-related scientific research.
A research project supervised by and closely related to the research program of a faculty member. The research project involves experimental design, data collection and analysis, written report and oral presentation. Students will be required to attend seminars and tutorials on topics related to research. Limited enrolment.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
A detailed description of the processes of heredity in bacteria including a discussion of gene structure and evolution, gene expression and its control, the exchange of genetic material in the microbial world and genetic engineering and its applications. The laboratory component will emphasize modern approaches to genetic engineering. (Offered in alternate years to MICR-835* and concurrently with MICR-436* with additional work required.) Winter term, two hours lecture, one hour tutorial. Not Offered 2010-2011.
Further study of contemporary virology using the textbook as a guide to particles, genomes, replication, expression, infection, and pathogenesis. Emphasizing reading and writing to develop skills in observation and critical thinking, important attributes in understanding the scientific method. (Offered in alternate years to MICR-851* and concurrently with MICR-450* with additional work required.) Fall term, three lecture hours, three seminar hours. E. Carstens. Not Offered 2010-2011.
The general principles and mechanisms of immune reaction. Immunochemical and immunobiological aspects of antibody formation and cell-mediated immunity in health and disease will be considered. (Offered concurrently with MICR-360* with additional work required.) Fall term, three lecture hours. M. Szewczuk
A required course for all graduate students entering a MSc or PhD from a BSc. Credit will be based upon attendance and participation in the weekly departmental seminar program and on attendance at all Visiting Speaker/Departmental seminars. In addition, each student will be required to present two seminars based upon his/her research work. Departmental faculty will provide evaluation of each student presentation consisting of a mark and written comments. A final mark will be compiled by the Graduate Program Coordinator (40%, first seminar; 60% second seminar). Fall and winter terms, seminar. N. Martin.
A comprehensive course emphasizing the major microbial and viral groups occurring in human and animal disease. The basic mechanisms involved in host-parasite interrelationships as well as current effective methodology used in their control will be studied. Winter term. N. Martin.
An integrated course dealing with microbial physiology as approached from biochemical, genetic and ecological perspectives. The course will also stress microbial diversity. Fall term. Three lecture hours. K. Poole.
Advanced general virology with a special emphasis on virus structure, replication patterns under permissive conditions and in persistent infections. Molecular aspects of gene duplication, expression and modulation are emphasized, as well as a consideration of viruses as expression vectors. Fall term. Three lecture hours. L. Raptis. Not Offered 2010-2011.
An advanced course emphasizing the main areas of contemporary immunology. Fall term. S. Basta.
A required course for all graduate students entering a Master¿s program and for those entering a doctoral program without a prior Master¿s of Science degree. Students will complete essays on central questions related to their research program. The intent of this course is to promote an early appreciation of the literature and/or experimental approaches germane to the student¿s proposed studies and/or address weaknesses/gaps in the student¿s prior studies that might impede his/her undertaking the proposed work. Offered all terms. K. Poole.
Fundamental properties of the nervous system. Emphasis placed on the properties of neurons that are fundamental to neuron-to-neuron communication, the formation of neural circuits, and the repair of the nervous system following injury. Tutorials introduce techniques and neurological problems that illustrate principles of neural function.
Fundamental properties of the nervous system. Emphasis placed on the properties of neurons and neural circuits that underlie behaviour and cognitive functions within selected neural systems, such as sensory, motor, reward, and autonomic systems. Tutorials introduce techniques and neurological problems that illustrate principles of neural function.
This course will provide an introduction to the main modelling approaches and theoretical concepts in Neuroscience. The computational anatomy of the brain and how it implements perception, learning, memory, decision making and motor control, among other topics, will be discussed.
RECOMMENDATION NSCI 323/3.0, NSCI 324/3.0, ANAT 312/3.0, PSYC 271/3.0.
This course covers the theory and practice of modern neuroimaging methods. Topics include data acquisition, research study design, and analysis methods. Functional MRI is presented in the most depth, but computed tomography (CT), positron emission tomography (PET), and single photon emission computed tomography (SPECT), are also covered.
LEARNING HOURS 120 (36L;84P)
A contemporary and comprehensive assessment of the neurochemical anatomy and neuropharmacology of the mammalian and human nervous systems as they relate to development, function and disease. Topics will include dynamics of neurotransmitter interactions, neuronal drug receptor interactions and second messengers, neurotoxicity associated transmitters and neural growth factors.
NOTE BMCO students should contact the Department regarding prerequisites.
A course providing 1) the essentials in cellular and molecular neuroscience to pursue a graduate program and/or a career in neuroscience or related field, and 2) independent learning and communication skills applicable broadly. The course is divided into three segments: 1) neuronal integration, 2) synaptic plasticity, and 3) neuromodulation.
NOTE BMCO students should contact the Department regarding prerequisites.
LEARNING HOURS 119 (12L;24S;8G;6I;69P)
A multi-disciplinary course exploring advanced concepts of clinical neuroscience. Topics include stroke, traumatic brain and cord injuries, neurodegenerative disorders, epilepsy, schizophrenia, depression, deep brain stimulation, pain and placebo effects, normal and abnormal aging, stem cells. Students will learn to critically evaluate scientific literature and present these concepts to classmates during student-led seminars. Restricted to fourth-year students. Enrollment is limited.
Cellular dysfunction is a critical feature of neural injury and disease among humans. This course will examine the cellular elements of the mammalian central and peripheral nervous system, with an emphasis placed on understanding normal and abnormal cellular function in both humans and animal models.
NOTE Restricted to students registered in the 4th year.
LEARNING HOURS 114 (36L;36Lb;42P)
As insight regarding the human brain expands, so do related issues such as what constitutes personhood, what drives the criminal mind, intelligence-enhancing drugs and end-of-life issues. Lead by experts who deal daily with such concerns, we will focus weekly on a particular topic in neuroscience which impacts on society.
LEARNING HOURS 108 (12L;24S;72P)
An exploration of brain systems underlying how the we learn and remember, and how they become disordered. Online multimedia modules and study of cutting edge research articles reveal how modern techniques and ideas are driving neuroscience forward. Requires interviewing a person with a disorder in order to learn to advocate for them in society.
Laboratory course in a selected area of Neuroscience to be arranged in consultation with individual members of the Centre for Neuroscience Studies. Course involves experimental design, data collection and analysis (approximately 6 hours of laboratory work per week required) as well as a brief communication of the laboratory work.
NOTE Students are limited to one NSCI 491/3.0 research project in Year 4.
NOTE Students whose research project requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
An investigation into a selected area of neuroscience. The research project involves experimental design, data collection, and analysis, written report and oral presentation. Students will be required to attend seminars and tutorials on topics related to research. Limited enrolment.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
An advanced course that will focus on current research topics in selected areas of Neuroscience. Topics will include research in all fields of specialization within the Neuroscience graduate program (Cellular/Molecular Neuroscience, Systems Neuroscience, Cognitive/Behavioural Neuroscience, Neurological and; Psychiatric Disorders) to introduce students to the breadth of research in Neuroscience. This course is required for all M.Sc. students in the Neuroscience graduate program.Three hour seminar/week: fall. TBA
This is a tutorial-based introduction to quantitative methods for neuroscience research. The goal is to provide Matlab/Python-based hands-on skills in signal processing, basic and advanced statistics, data neuroscience (machine learning) and model fitting methods. This includes an introduction to scientific programming as well as causality-supporting methods and open science framework approaches.
This course is designed for graduate students who want to learn the theory and practice of magnetic resonance imaging (MRI) for anatomical imaging, imaging of dynamic physiological processes, and MRI to detect neuronal function (functional MRI, fMRI). The course will allow the student to gain an understanding of the principles that underlie the applications of MRI and fMRI as a research tool.Three hour lecture/week; fall. P. Stroman
Recent advances in understanding neurotransmission and pharmacology in the central nervous system will be discussed. The current literature describing progress in understanding molecular, cellular and behavioural aspects of brain function, and the impact of drugs and disease, will be examined. Winter; seminars. Given in years ending with an uneven number.
PREREQUISITE: Permission of Graduate Program
EXCLUSION: PHAR-810*, BMED-813*
Designed for students with special interests that are not covered by existing courses offered in the Centre for Neuroscience Studies. Normally, this will take the form of a closely supervised reading course in the area of a graduate instructor's expertise, but may also include supervised laboratory work and/or specialized clinical experience. A plan of study must be approved by course coordinator.
An in-depth study of the biophysical properties of neurons and diseases that affect the function of neurons and glia. (same as ANAT 822 and PHGY 822) Topics will include cable properties of dendrites, voltage- and ligand-dependent channels, and molecular mechanisms responsible for neuronal death and regeneration. The course will be based on lectures and student seminars of selected readings. Given concurrently with LISC-422*, with additional assignments for graduate students.One hour lecture/week, 2 hour seminar/week: winter. K. Rose. (Offered in years ending in an even number)
A multidisciplinary graduate level course exposing students to the clinical aspects of neuroscience . Didactic lectures cover detailed organization of the nervous system with clinical implications. Laboratories review basic neuroanatomy and pathology. Clinical demonstrations expose students to several neurological disorders. Lectures, laboratories, and clinical cases.
A course for graduate students to explore advanced concepts of cognitive processes in the central nervous system. This is a multi-disciplinary lecture/seminar course with active student participation expected. The course will consist of weekly sessions focusing on specific concepts such as perception, motor processing, reward systems, working memory, executive functions and decision making. Offered jointly with NSCI-426.
PREREQUISITE: Permission of Instructor
EXCLUSION: ANAT-826*, PHGY-826*
A multi-disciplinary course exploring advanced concepts of clinical neuroscience . Topics can include stroke, traumatic brain and cord injuries, neurodegenerative disorders, epilepsy, schizophrenia, depression, deep brain stimulation, pain and placebo effects, normal and abnormal aging, stem cells. Students will learn to critically evaluate scientific literature and present these concepts to classmates during student-led seminars. Enrolment is limited.
Alzheimer¿s disease and related dementias will have an increasing importance in the field of neuroscience given the aging of the Canadian population. The purpose of this course is to provide an overview of the major topic areas in dementia research and provide a foundation for understanding the complexity of dementia research across disciplines and research methodologies.
As insight regarding the human brain expands, so do related issues such as what constitutes personhood, what drives the criminal mind, intelligence-enhancing drugs and end-of-life issues. Lead by experts who deal daily with such concerns, we will focus weekly on a particular topic in neuroscience which impacts on society.
PREREQUISITE: At minimum, an introductory course in the Neurosciences or permission of the Instructor.
This course will provide an overview and hands on experience of the most important computational approaches in Neuroscience. The main topics covered include single cell and neural network modelling, Bayesian approaches, State Space modelling and Optimal Control Theory. More specific modelling approaches will also be discussed as well as some widely used computational data analysis methods.
This course is based on the annual Summer School in Computational Sensory-Motor-Neuroscience (CoSMo), which is a 2-week (12 days) intensive course. Through lectures, tutorials and a problem-based project, students will gain advanced knowledge and experience in the application of computational methodologies to modelling in neuroscience.
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in clinical neuroscience methods involved in biomedical research. (Weight= 1.0 credit unit) EXCLUSION: BMED-868
The course provides an introduction to human disease and our understanding of key conditions with major global health and societal impact, including cardiovascular, neurological and infectious diseases and cancer. The basic concepts of disease mechanisms and current management will be explored using specific diseases and clinical example cases.
Also offered online.
LEARNING HOURS may vary 120(12L;36G;36O;36P)
An introduction to pathology and molecular medicine. The course will be organized around a specific set of diseases, designed to illustrate basic concepts in the molecular biology, biochemistry, and pathology of human disease.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
PATH 381 covers advanced topics of biochemistry and analytical chemistry in relation to the practice of clinical biochemistry in healthcare. Students will critique how laboratory principles, biochemistry, and analytical techniques are applied to practical medical problems in the context of various diseases. Through problem-based learning approaches, students will gain experience in identifying and troubleshooting issues in laboratory testing as well as the integrated role of clinical biochemists within a healthcare team.
The course introduces data science tools and methods to handle, process and extract knowledge and insights from large molecular medicine datasets. The focus will be on applying statistics, machine learning and related methods for the analysis of various research datasets and digital pathology.
LEARNING HOURS 120(18L12pC;84G;6O;36P)
An advanced level course introducing current topics in human genetics. The course will focus on the significance and implications of genetic variation and its role in disease, development and normal human diversity. In particular, the course will explore the future directions and implications of human genetic research in the post genomic era. Participation in seminars and group discussions is required. Enrollment is limited.
RECOMMENDATION BCHM 218/3.0 or MBIO 218/3.0 or permission of the course coordinator.
An in-depth perspective of the pathogenesis of human disease. An integration of the genetic, biochemical, physiologic, anatomic, and general etiologic factors which play a role in the progression of several specific diseases from inception to death or recovery. The course will comprise short introductory presentations by teaching faculty followed by the presentation and discussion of relevant scientific papers by students. Given jointly with PATH 826/3.0.
A research project involving the study of human disease processes. The project will be supervised by a Faculty member in the Department and will provide opportunities for experimental design, data analysis and both written and oral presentation of results. Students must contact a potential faculty supervisor in the Spring preceding registration in fourth year.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
Intended for students engaged or interested in pre-clinical cancer research. Both medical and basic science trainees are encouraged to take this course. Specific areas to be covered include introduction to new drug development, molecular basis of oncogenic transformation and signalling pathways, challenges with current cancer therapeutics, molecular approaches to profiling human cancers as tools for identifying biochemical and genetic abnormalities and developing criteria for reliable prognostic indicators; strategies for novel target and drug discovery, as well as experimental drug delivery; novel imaging approaches to enhance the sensitivity of preclinical testing and selection of responsive patients; preclinical (in vitro and animal) models for validating experimental targets; clinical drug development and testing of novel anti-cancer drugs; and the molecular basis for variability in tumour responses. Half course, lectures and seminars; fall term. C. Nicol
The aim of this course is to introduce and discuss essential questions in the basic science of oncology. Trainees with an interest in cancer research are encouraged to take this course. Topics include pathology of cancer, cancer genetics, growth factors, signal transduction, oncogenes, suppressor genes, early stage tumorigenesis, tumor immunology and metastasis. A general theme for the course will be mechanisms regulating neoplastic transformation and tumor progression. In order to provide a balance and high profile in all areas, various staff members in the Cancer Research Institute and associated departments have been selected as session leaders in this course. Half course, lectures and seminars; fall term. B. Elliott.
This course covers several diseases that highlight the genetic, biochemical, physiologic, anatomic, and general etiologic factors that play a role in the progression of each disease from its inception to death or recovery. Some of the topics will be drawn from the ongoing research within the Department of Pathology and Molecular Medicine. The perspective will demonstrate that each disease is the result of an evolving interplay of genetic and environmental factors. (Jointly with PATH-430*. Additional work prescribed for graduate students.) Half-course, lectures and seminars; Winter term. D. Lillicrap.
Research projects in the physiological, biological, genetic and molecular basis of disease. Students will review the literature related to their proposed graduate research thesis project and write a series of essays on topics selected in consultation with a supervisory committee consisting of their supervisor and two other faculty. They will also develop a written draft research proposal that will be presented to their supervisory committee and defended in a final oral examination. To be taken by all students in the first full term of the graduate program. P.Greer (course coordinator).
Bioinformatics is an essential component of biological and health science research given the ongoing developments in generating large amounts of data in short periods of time. This course introduces tools and methods to manage and analyze the results obtained in cancer research. Topics include study design, basic statistics for clinical and genetic research, data-mining approaches and alternative methods to statistics for data analysis, and signaling pathways analysis. The course will cover the appropriate pre-processing and data analysis techniques for various genetic data types such as microarray, tissue microarrays, methylation, NanoString, RNAseq, miRNAseq, proteomics and qRT-PCR. Students with little computing background, but who are interested in pursuing or collaborating with bioinformatic research, are encouraged to enroll.
This seminar series consists of weekly presentations by visiting external speakers, Queen's faculty, and Departmental MSc and PhD students. MSc students will give 1/2 hour seminars in their first year, and one hour seminars in their second year; PhD students will give 1 hour seminars in their first and third years, and an exit seminar in their final year. Attendance by all Departmental graduate students is compulsory and will be monitored by the Graduate Program Coordinator. Departmental faculty will provide evaluations of student presentations. Only one mark will be assigned, based on the average of the student's first two seminars. If a grade is submitted for Path 830, a second rading for Path 930 is unnecessary.
Pathology and Molecular Medicine Research Seminar Series
This seminar series consists of weekly presentations by visiting external speakers, Queen's faculty, and Departmental MSc and PhD students. MSc students will give 1/2 hour seminars in their first year, and one hour seminars in their second year; PhD students will give 1 hour seminars in their first and third years, and an exit seminar in their final year. Attendance by all Departmental graduate students is compulsory and will be monitored by the Graduate Program Coordinator. Departmental faculty will provide evaluations of student resentations. Only one mark will be assigned, based on the average of the student's first two seminars. If a grade is submitted for Path 830, a second grading for Path 930 is unnecessary.
Topics covered include central nervous system stimulants and depressants, narcotics, alcohol, cardiovascular agents, contraceptives, environmental toxicants, mechanism of drug action and disposition, antibiotics, drugs used in sports, over-the-counter drugs, food additives, and vitamins.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office. Learning Hours may vary.
Lecture series on the following topics: principles of drug action, autonomic pharmacology, cardiovascular-renal pharmacology, neuropsychopharmacology, chemotherapy, drugs acting on the endocrine system, over-the-counter drugs, and therapeutic applications.
LEARNING HOURS 122 (36L;8G;78P)
Topics include: fundamental principles of drug action, autonomic nervous system pharmacology, and toxicology.
LEARNING HOURS 120 (27L;24T;69P)
An interdisciplinary course that introduces the basic principles and clinical applications of pharmacology. This 12-week course covers six topics. Students will work through the topics online, using a combination of online modules, readings, and short video clips. Students will participate in a variety of assessments throughout the course.
LEARNING HOURS may vary: 120(48O;72P)
Also offered online.
This course will explore the human toxicology associated with both pharmaceutical and environmental exposures. Topics include metabolism and mechanisms of toxicity of various pharmaceuticals and environmental pollutants. Toxicological effects of specific classes of environmental toxicants and different groups of pharmaceuticals are also discussed.
NOTE Also offered online. Consult Bachelor of Health Sciences program office.
LEARNING HOURS may vary 120 (60O;60P)
An advanced study of chemical disposition and toxicity. Topics include toxicokinetics, biotransformation, metabolite-mediated toxicity, free radicals, the mechanism of action of toxicants, effects of toxicants on organ systems and a detailed examination of selected toxic agents.
NOTE BCHM, BIOL, BMCO ELSC and ETOX students should contact the department for permission to enrol in this course.
LEARNING HOURS 120 (36L;84P)
Topics include: neuropsychopharmacology, cardiovascular pharmacology, agents acting on the endocrine system, and chemotherapy.
NOTE This course involves team based learning sessions and a drug literature evaluation assignment.
This survey course covers the life-cycle of pharmaceutical products including discovery, development, and the transition to a generic or over-the-counter medication. Specific themes include target identification, design and synthesis, efficacy determination, optimization, preclinical safety assessment, clinical trials, and the differences between biologics and small chemical entities. Social and economic pressures exerted upon the pharmaceutical industry are also explored.
An examination of the development and present state of knowledge in selected research areas of pharmacology and toxicology. Research project involves experimental design, data collection and analysis, written report and oral presentation. Students will be required to attend seminars and tutorials on topics related to research.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
Recent advances in understanding neurotransmission and pharmacology in the central nervous system will be discussed. The current literature describing progress in understanding molecular, cellular and behavioural aspects of brain function, and the impact of drugs and disease, will be examined. Winter; seminars and tutorials. Given in years ending with an uneven number. J.N. Reynolds
An advanced course in which various aspects of the drug discovery and development process, from molecules to community, will be studied. The course comprises lectures, discussion and student seminars, based on recent literature. Topics encompass medicinal chemistry approaches to drug discovery, receptor theory, mechanisms of drug action, drug metabolism, pharmacokinetics, pharmacogenetics, drug resistance, clinical trials, and regulatory affairs. Fall, 3 hour seminar. Given in years ending with an even number. T.E. Massey
An advanced, problem-based course focusing on current approaches to the study of mechanisms of chemical toxicity. Winter; 3 hour seminars and tutorials. Given in years ending with an even number. T.E. Massey
Topics covered: selected topics in pharmacology and toxicology will be presented and discussed by staff, students, and visiting lecturers. Fall and winter; one hour per week. J.F. Brien
This is an introductory level course on the structure and function of human cells for students interested in pursuing human health-related disciplines. Students will also learn the principles of energy metabolism, cell growth and proliferation, and how cells interact with their environment. There is also an overall focus to relate cellular processes to human function and disease, culminating in a group presentation focused on one specific cell process and how it affects health. Students taking this course will be well-prepared for upper year molecular biology courses.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office. Learning Hours may vary.
LEARNING HOURS may vary 114 (36O;78P)
The focus of this course is on the central and peripheral nervous systems, muscle physiology, the heart, and the vascular system.
NOTE This course may be paired with PHGY 216/3.0 to achieve an introductory physiology full course (6.0 units).
NOTE Although it is recommended to take PHGY 215/3.0 first, this course can be taken before, after, or concurrently with PHGY 216/3.0.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office. Learning Hours may vary.
The focus of this course is the physiology of the respiratory, renal, gastrointestinal, endocrine, and reproductive system.
NOTE This course may be paired with PHGY 215/3.0 to achieve an introductory physiology full course (6.0 units).
NOTE Although it is recommended to take PHGY 215/3.0 first, PHGY 216/3.0 can also be taken before or concurrently with PHGY 215/3.0.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office.
Learning hour may vary.
This course is designed to advance critical thinking and practical lab skills through collaborative experimentation on human physiological responses to various stimuli. Upon completion, students should be able to (i) plan and perform experimental protocols, (ii) collect, analyze and interpret data and (iii) produce quality presentations of findings.
LEARNING HOURS 120(36Lb;48O;36P)
An introductory course in Pathophysiology in which the underlying functional changes of cell and cell systems will be discussed in association with a variety of disease processes.
LEARNING HOURS 114 (36L;6O;72P)
An intermediate course focusing on biomedical applications of lung biology. Topics include lung mechanics, gas exchange, acid-base balance and control of breathing.
PHGY 370, Pathophysiology is an introductory course in which the underlying functional changes of cells and physiological systems will be discussed in association with a variety of disease processes. This course builds on the knowledge and concepts learned in prerequisite physiology courses and uses that foundation to understand how human disease disrupts the function of the major systems of the body, and to a lesser degree, how it is diagnosed and treated.
The electrophysiology and biophysics of neuronal and cardiac membranes; molecular biology, structure, and function of ion channels. Students will learn to critically evaluate scientific literature. Instructional format is primarily student-led seminars.
Cellular and molecular approaches to human intestinal function are described and synthesized into an understanding of intestinal physiology at the organ level. Taught by GI researchers and clinician-scientists; students prepare and present critical appraisals of current primary research papers.
Students are exposed to an in depth study of selected topics in neuroendocrinology and neuroendocrine techniques. Neuroendocrinology refers to the neural control of endocrine and autonomic function. Areas of focus will include central nervous system control of cardiovascular function, reproduction, and appetite. In addition, students will learn to critically evaluate scientific literature. Instructional format is primarily student led seminars.
LEARNING HOURS 114 (36S;12O;96P)
An investigation in a selected area of physiology. The project involves experimental design, data collection and analysis, submission of written reports, and oral presentations. Students attend seminars/tutorials on related topics.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).
An advanced course on current research of selected areas of physiology. This course is comprised of critical lectures and discussion based on recent literature. Compulsory for all new graduate students in Physiology. Winter term; 3 hour seminar.
The electrophysiology and biophysics of neuronal and cardiac membranes; molecular biology, structure, and function of ion channels. Students will learn to critically evaluate scientific literature. Instructional format is primarily student-led seminars. N. Magoski. Enrolment is limited. (Offered even years only jointly with PHGY 424).
A course for graduate students to explore more advanced concepts of sensorimotor integration in the nervous system. This is a multi-disciplinary lecture/seminar course with active student participation expected. The course will consist of weekly sessions focusing on specific concepts such as feature detection, population coding, sensorimotor transformations, reflexes versus voluntary control, central pattern generators. Normally offered concurrently with PSYC-924*. Winter term; 1 hour lecture; 2 hour seminar/discussion. M. Dorris. Not offered 2010-2011.
An advanced course for honours and graduate students in which selected areas of physiology are studied in depth. Two hours seminar. S. Iscoe.
A laboratory-based course providing an advanced survey of state-of-the-art methodologies. This course is designed to give the student experience in cellular, molecular and whole tissue techniques with applications to digestive and related sciences. Fall term; 2 hours seminar / 4 hours laboratory on alternate weeks. R.J. MacLeod. Not offered 2010-2011.
A laboratory-based course designed to explore in greater depth a sub-group of the techniques studied in PHGY-840* and involving at least two full weeks of intensive laboratory work. The techniques will be chosen to complement the student's graduate research. Winter or Spring/summer term. R.J. MacLeod. Not offered 2010-2011.
The mechanisms and regulation of motor, secretory, digestive and absorptive functions of the gastrointestinal tract are considered. Students will be required to prepare and present reviews of original literature. Fall/winter terms. (Enrolment in both terms is required to achieve credit.) One hour lecture/week; 1 hour seminar alt. wks. M. Blennerhassett. Offered jointly with PHGY-444.
Students are exposed to an in depth study of selected topics in neuroendocrinology and neuroendocrine techniques. Neuroendocrinology refers to the neural control of endocrine and autonomic function. Areas of focus will include CNS control of cardiovascular function, reproduction, and appetite. In addition, students will learn to critically evaluate scientific literature. Instructional format is primarily student- led seminars. (Offered jointly with PHGY-494). Winter term. D. Van Vugt.
Students will be required to attend the Departmental seminar program and present a seminar based upon their graduate thesis research. Students will also provide a proposal for their thesis research which includes a review of the related literature. Departmental faculty will evaluate both the seminar and the proposal/review. Enrolment extending over 6 terms (2 years; required for new Master¿s level Physiology graduate students. 1 hour seminar/week; Fall, Winter and Spring/Summer. N. Magoski.
Students will obtain a general background on various aspects of human reproduction, ranging from male and female gamete development to pregnancy and birth. The course will serve as a gateway to more advanced courses in human reproduction and development.
NOTE Also offered online. Consult the Bachelor of Health Sciences program.
LEARNING HOURS may vary 120 (60O;60P)
This course will be focus on, 1. Common and rare reproductive pathologies with sex and gender associated susceptibilities and disease outcomes. 2. Role of sexual dimorphism in etiology, pathogenesis and immune responses of reproductive diseases. 3. Conventional and advanced tools in diagnosis and treatment of reproductive diseases.
LEARNING HOURS 120 (24L;12S;36G;48P)
Comprehensive overview of cellular and molecular biology of mammalian
reproduction including gametogenesis, fertilization, early embryo development and placentation; selected topics of clinical aspects of reproduction. Participation in seminars and group discussion is required.
LEARNING HOURS 120 (36L;36S;48P)
REPD 473, Development Origins of Health and Disease, will cover how the early-life environment contributes to later-life health. Four major topics will be covered: maternal exposures, maternal nutrition, infection, and pregnancy complications. Students will learn about how alterations in the embryonic and fetal environment due to these four parameters can and do contribute to the development of non-communicable diseases that persist throughout life. Students will have the opportunity to explore and consolidate the academic literature pertaining to DOHaD, as well as investigating the resources available to these populations of patients.
An examination of the development and present state of knowledge in selected research areas of Reproduction and Development. Research project involves experimental design, data collection and analysis, written report, poster presentation and oral presentation. Students will be required to attend seminars and tutorials on topics related to research.
NOTE Limited enrolment; restricted to 4th year honours; permission of the Department required. Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (24L;48S;192Lb;168P)