Academic Calendar 2021-2022

Pharmacology & Toxicology (PHAR)

PHAR P10  Drugs & Their Actions  Units: 3.00  

Offering Faculty: Faculty of Health Sciences  
PHAR 100  Introductory Pharmacology  Units: 3.00  

Topics covered include central nervous system stimulants and depressants, narcotics, alcohol, cardiovascular agents, contraceptives, environmental toxicants, mechanism of drug action and disposition, antibiotics, drugs used in sports, over-the-counter drugs, food additives, and vitamins.
NOTE Also offered online. Consult the Bachelor of Health Sciences program office. Learning Hours may vary.

Requirements: One-Way Exclusion PHAR 230/3.0; PHAR 270/3.0; PHAR 340/3.0; PHAR 370/3.0; PHAR 450/3.0  
Offering Faculty: Faculty of Health Sciences  
PHAR 230  Pharmacology for the Health Sciences  Units: 3.00  

Lecture series on the following topics: principles of drug action, autonomic pharmacology, cardiovascular-renal pharmacology, neuropsychopharmacology, chemotherapy, drugs acting on the endocrine system, over-the-counter drugs, and therapeutic applications.
LEARNING HOURS 122 (36L;8G;78P)

Requirements: Co PHGY21# Exclusion  
Offering Faculty: Faculty of Health Sciences  
PHAR 340  Principles of General Pharmacology I  Units: 3.00  

Topics include: fundamental principles of drug action, autonomic nervous system pharmacology, and toxicology.
LEARNING HOURS 120 (27L;24T;69P)

Requirements: PREREQUISITE (PHGY 215 and PHGY 216) or BIOL 339 or PHGY 210 or PHGY 214 EXCLUSION No more than 3.0 units from PHAR 230; PHAR 270; PHAR 340; PHAR 370.  
Offering Faculty: Faculty of Health Sciences  
PHAR 341  General Pharmacology  Units: 3.00  

Requirements: BCHM315 OR BCHM310  
Offering Faculty: Faculty of Arts and Science  
PHAR 370  Fundamentals of Pharmacology and Therapeutics  Units: 3.00  

An interdisciplinary course that introduces the basic principles and clinical applications of pharmacology. This 12-week course covers six topics. Students will work through the topics online, using a combination of online modules, readings, and short video clips. Students will participate in a variety of assessments throughout the course.
LEARNING HOURS may vary: 120(48O;72P)
Also offered online.

Requirements: Corequisite One of (PHGY 215/3.0 and PHGY 216/3.0) or KNPE 225/3.0. Exclusion PHAR 230/3.0; PHAR 270/3.0; PHAR 340/3.0 One-Way Exclusion PHAR 450/3.0  
Offering Faculty: Faculty of Health Sciences  
PHAR 380  Drug and Environmental Toxicology  Units: 3.00  

This course will explore the human toxicology associated with both pharmaceutical and environmental exposures. Topics include metabolism and mechanisms of toxicity of various pharmaceuticals and environmental pollutants. Toxicological effects of specific classes of environmental toxicants and different groups of pharmaceuticals are also discussed.
NOTE Also offered online. Consult Bachelor of Health Sciences program office.
LEARNING HOURS may vary 120 (60O;60P)

Requirements: Minimum 3rd year (Level 3) standing and one of (BCHM 270/3.0; BCHM 316/3.0; BCHM 218/3.0; BIOL 334/3.0).  
Offering Faculty: Faculty of Health Sciences  
PHAR 416  Xenobiotic Disposition and Toxicity  Units: 3.00  

An advanced study of chemical disposition and toxicity. Topics include toxicokinetics, biotransformation, metabolite-mediated toxicity, free radicals, the mechanism of action of toxicants, effects of toxicants on organ systems and a detailed examination of selected toxic agents.
NOTE BCHM, BIOL, BMCO ELSC and ETOX students should contact the department for permission to enrol in this course.
LEARNING HOURS 120 (36L;84P)

Requirements: PREREQUISITES (PHAR 340 or BCHM 310 or BCHM 316 or BIOL334) and Level 4 and a GPA of 2.5.  
Offering Faculty: Faculty of Health Sciences  
PHAR 450  Principles of General Pharmacology II  Units: 3.00  

Topics include: neuropsychopharmacology, cardiovascular pharmacology, agents acting on the endocrine system, and chemotherapy.
NOTE This course involves team based learning sessions and a drug literature evaluation assignment.

Requirements: Prerequisite (PHAR 230 or PHAR 270 or PHAR 370 with a min grade of B) or PHAR 340.  
Offering Faculty: Faculty of Health Sciences  
PHAR 480  Drug Discovery and Development  Units: 3.00  

This survey course covers the life-cycle of pharmaceutical products including discovery, development, and the transition to a generic or over-the-counter medication. Specific themes include target identification, design and synthesis, efficacy determination, optimization, preclinical safety assessment, clinical trials, and the differences between biologics and small chemical entities. Social and economic pressures exerted upon the pharmaceutical industry are also explored.

Requirements: Minimum 4th year (Level 4) standing and one of (PHAR 230/3.0; PHAR 370/3.0; PHAR 340/3.0). LISC MAJ SSP students require a GPA of 2.5. Note this course cannot be used as credit towards the LISC DDHT SSP Plan Exclusion DDHT 459/3.0; DDHT 460/3.0  
Offering Faculty: Faculty of Health Sciences  
PHAR 499  Research Project in Pharmacology and Toxicology  Units: 12.00  

An examination of the development and present state of knowledge in selected research areas of pharmacology and toxicology. Research project involves experimental design, data collection and analysis, written report and oral presentation. Students will be required to attend seminars and tutorials on topics related to research.
NOTE Acceptance by a supervisor required prior to registration.
NOTE Students whose research requires the care and/or handling of animals must also complete the Introductory Animal Care Course and if required the appropriate Animal Use workshops through the Office of the University Veterinarian.
LEARNING HOURS 480 (288Lb;24G;24I;144P).

Requirements: Prerequisite Level 4 and registration in a LISC or ELSC Specialization Plan and a cumulative GPA of 2.50 or higher. Exclusion ANAT 499; CANC 499; EPID 499; LISC 499; MICR 455; MICR 499; NSCI 499; PATH 499; PHGY 499; REPD 499.  
Offering Faculty: Faculty of Health Sciences  
PHAR 799  Introduction To Animal Care  Units: 6.00  

Offering Faculty: Faculty of Health Sciences  
PHAR 810  Advances In Neuropharmacology  Units: 3.00  

Recent advances in understanding neurotransmission and pharmacology in the central nervous system will be discussed. The current literature describing progress in understanding molecular, cellular and behavioural aspects of brain function, and the impact of drugs and disease, will be examined. Winter; seminars and tutorials. Given in years ending with an uneven number. J.N. Reynolds

Requirements: PHAR450 OR LISC322  
Offering Faculty: Faculty of Health Sciences  
PHAR 811  Drug Discovery & Development  Units: 3.00  

An advanced course in which various aspects of the drug discovery and development process, from molecules to community, will be studied. The course comprises lectures, discussion and student seminars, based on recent literature. Topics encompass medicinal chemistry approaches to drug discovery, receptor theory, mechanisms of drug action, drug metabolism, pharmacokinetics, pharmacogenetics, drug resistance, clinical trials, and regulatory affairs. Fall, 3 hour seminar. Given in years ending with an even number. T.E. Massey

Requirements: BCHM310  
Offering Faculty: Faculty of Health Sciences  
PHAR 814  Princ Of Analyt. Toxicology I  Units: 3.00  

Offering Faculty: Faculty of Health Sciences  
PHAR 815  Mechanistic Toxicology  Units: 3.00  

An advanced, problem-based course focusing on current approaches to the study of mechanisms of chemical toxicity.  Winter; 3 hour seminars and tutorials.  Given in years ending with an even number.  T.E. Massey

Requirements: BCHM310  
Offering Faculty: Faculty of Health Sciences  
PHAR 821  Pharmacology Seminar  Units: 3.00  

Topics covered: selected topics in pharmacology and toxicology will be presented and discussed by staff, students, and visiting lecturers. Fall and winter; one hour per week. J.F. Brien

Offering Faculty: Faculty of Health Sciences  
PHAR 999  Ph.D. Thesis Research  Units: 6.00  

Offering Faculty: Faculty of Health Sciences