Academic Calendar 2022-2023

Biomedical and Molecular Sciences

BMED 804     Clinically Oriented Anatomy     
A detailed study of the gross and functional anatomy of the human body with emphasis on clinical application. The course is given jointly with part of Phase I of the medical curriculum. Additional work prescribed for graduate students. Full course; lectures, laboratories and tutorials. L.W. MacKenzie. 
EXCLUSION: ANAT 814

BMED 805     Microteaching in Anatomical Sciences     
Microteaching as a technique for new and experienced teachers will involve the presentation of a series of 3 minute micro lectures with video recording and feedback sessions. L.W. MacKenzie. 
EXCLUSION: ANAT 835

BMED 806     Advanced Topics in Embryonic Development     
This half credit course will be offered to students who have completed ANAT 417 in their undergraduate studies in the Queen's Life Sciences Program. Through a series of tutorials and seminars, the course will focus on the most up to date discoveries in three areas of developmental biology. The areas reflect the expertise in the department. Winter term; Instructor TBD. 
EXCLUSION: ANAT 836

BMED 807     Current Topics in Anatomy and Cell Biology     
The topics will be chosen on the basis of special needs of the students, and must be approved by the Coordinator of Graduate Studies. Seminars.  Not offered in 2022-23. 
EXCLUSION: ANAT 926

BMED 809     Principles of Drug Discovery and Development     
An advanced course in which various aspects of the drug discovery and development process, from molecules to community, will be studied. The course comprises lectures, discussion and student seminars, based on recent literature. Topics encompass medicinal chemistry approaches to drug discovery, receptor theory, mechanisms of drug action, drug metabolism, pharmacokinetics, pharmacogenetics, drug resistance, clinical trials, and regulatory affairs. 3 hour seminar. Winter term. Given in years ending with an odd number. Fall term; L. Winn.
PREREQUISITE:  Permission of the Graduate Program required.  Not offered in 2022-23.
EXCLUSION: PHAR 811

BMED 810     Protein Structure and Function     
This course presents an integrated approach to the study of protein function.  Topics include proteomic techniques in protein profiling, mass spectrometry, 2 D gel electrophoresis, yeast 2 hybrid analysis, protein chips, protein purification, imaging, surface plasmon resonance, calorimetry, bioinformatics and protein evolution, protein modifications and processing, interpretation and applications of 3 D structure, protein structure function relationships. Offered jointly with BCHM 410 with additional work required. Three lecture hours per week. Fall term. Z. Jia.
PREREQUISITES:  BCHM 310 or 315 /316 /317 or permission of the instructor.  
EXCLUSION: BCHM 410, BCHM 810    

BMED 811     Advanced Molecular Biology     
This course concentrates on the molecular biology of mammalian models particularly mechanisms involved in human diseases. The human genome project, forensic analysis, DNA diagnostics of human diseases, models of transcriptional and growth regulation and cancer, DNA repair, RNA processing and translation are all discussed. Emphasis on recent findings and course materials will be drawn from current reviews. Three lecture hours per week. (Offered jointly with BCHM 411 with additional work required.) Winter term.
PREREQUISITE: BCHM 310 or 315 /316 /317 or permission of the instructor   
EXCLUSION: BCHM 411, BCHM 811.      

BMED 812     Advanced Neuroanatomy     
This course includes the study of the structure and general function of the nervous system and is given jointly with ANAT 312 . Special topics assigned for seminars and essay projects. Fall term; lectures, laboratories and seminars. L. Mackenzie
EXCLUSION: ANAT 812

BMED 813     Advances in Neuropharmacology     
Recent advances in understanding neurotransmission and pharmacology in the central nervous system will be discussed. The current literature describing progress in understanding molecular, cellular and behavioural aspects of brain function, and the impact of drugs and disease, will be examined. Seminars. Given in years ending with an odd number. Not offered in 2022-23.
PREREQUISITE: Permission of Graduate Program.
EXCLUSION: PHAR 810 , NSCI 813     

BMED 815     Mechanistic Toxicology     
An advanced, problem based course focusing on current approaches to the study of mechanisms of chemical toxicity. 3 hour seminars and tutorials. Given in years ending with an even number.  Winter term. T. Ozolins
PREREQUISITE: PHAR 416 or equivalent. Permission of the Graduate Program required.
EXCLUSION: PHAR 815    

BMED 816     Biology of Reproduction     
A comprehensive overview of the cellular and molecular biology of mammalian reproduction. The first part of the course consists of lectures covering gametogenesis, fertilization, early embryo development and placentation. The second part involves student presentation of seminars and group discussion of current topics in reproductive biology. Clinical aspects of reproduction will also be covered. Offered jointly with ANAT 416 . Graduate students submit one major essay and give a seminar from a list of selected topics. Three hours lecture/seminar, Fall term. F.W.K. Kan. Not offered in 2022-23.
PREREQUISITE: ANAT 215 /216 or ANAT 311, or ANAT 309 or permission of the Department.
EXCLUSION: ANAT 816

BMED 817     Mammalian Embryonic Development
Overview of mammalian development, emphasizing the cellular and molecular mechanisms that direct embryogenesis. The first 2/3 of the course consists of lectures on gastrulation, neurulation, establishment of the body axes, differentiation, sex determination, limb development, and organogenesis. The last 1/3 of the course involves student seminar presentations and group discussions of current topics in developmental biology and teratology. Offered jointly with ANAT 417 . Students submit a major essay and give a seminar from a selected list of topics. Three hours of lectures/seminars per week. Winter term; Instructor TBD. 
PREREQUISITE: ANAT 416/ANAT 816 , or BMED 816 , or permission of the Department.
EXCLUSION: ANAT 817    

BMED 818     Chemical Neuroanatomy     
A contemporary and comprehensive assessment of the neurochemical features of the mammalian nervous system as they relate to development, function and disease. 3 hour lecture/seminar.  Offered alternate years. Fall term; M. Kawaja.  Not offered in 2022-23.
PREREQUISITE: ANAT 312 or LISC 322 or permission of the Department.
EXCLUSION: ANAT 818

BMED 822     Cellular and Molecular Neuroscience       
An in depth study of the biophysical properties of neurons and diseases that affect the function of neurons and glia. Topics will include cable properties of dendrites, voltage and ligand dependent channels, and molecular mechanisms responsible for neuronal death and regeneration. The course will be based on lectures and student seminars of selected readings. Given concurrently with LISC 422 , with additional assignments for graduate students. Enrolment is limited. Winter term; E. Dumont. 
PREREQUISITE: LISC 322 with a minimum of B (70%) or an equivalent course or permission of the instructor.
EXCLUSION: ANAT 822
 
BMED 823 Scientific Communication
The goal of the course is to introduce new graduate students to the basic skills that will be necessary for them to acquire, organize and disseminate information as well as present it effectively. Students will present landmark cell biology papers with a focus on the molecular basis of human disease. (3.0 credit units).

BMED 824     Ion Channels of Excitable Cells     
The electrophysiology and biophysics of neuronal and cardiac membranes; molecular biology, structure, and function of ion channels. Students will learn to critically evaluate scientific literature. Instructional format is primarily student led seminars. Enrolment is limited. (Offered jointly with PHGY 424.) Winter term; N. Magoski.  
PREREQUISITES: PHGY 214 (or equivalent) with a minimum of 65 percent (or equivalent) or permission of the course supervisor. 
EXCLUSION: PHGY 824

BMED 825     Medical Neuroscience     
A multidisciplinary graduate level course exposing students to the clinical aspects of neuroscience. Didactic lectures cover detailed organization of the nervous system with clinical implications. Laboratories review basic neuroanatomy and pathology. Clinical demonstrations expose students to several neurological disorders. Didactic lectures, laboratories, and clinical cases (up to 20 hr/week; 9 weeks total.)  Winter term; M. Kawaja.
PREREQUISITES: Enrolment in graduate program and involvement in neuroscience research.
EXCLUSION: ANAT 825

BMED 827     Advanced Topics in Neuroanatomy     
This half credit course will be offered to students who have completed ANAT 312 in their undergraduate studies in the Queen's Life Sciences Program. Through a series of tutorials and seminars, the course will focus on the most up to date discoveries in three areas of neuroanatomy. The areas reflect the expertise in the department. Fall term; L. MacKenzie.
EXCLUSION: ANAT 837

BMED 828     Advanced Histology and Staining Techniques     
An advanced mammalian histology course including advanced staining protocols in demonstrating various components of Histological techniques. Winter and Summer terms; L.W. MacKenzie and S.C. Pang.
EXCLUSION: ANAT 838  

BMED 831     Cell Structure and Basic Tissues     
For those with no histology background, an outline of basic vertebrate tissues. Extra assignments will be given to graduate students. Fall term. Lectures and laboratories in common with ANAT 309 in Winter Term. L. Postovit.
EXCLUSION: ANAT 311, ANAT 309 , ANAT 831  

BMED 832     Molecular Basis of Cell Function     
This course provides an introduction to the signaling pathways that regulate key cellular functions such as growth and motility. The biochemical and structural principles that underlie the regulation of enzyme and protein activity in cells are emphasized. Topics include protein kinases and phosphatases, ubiquitin modification, G protein coupled receptors, growth factor receptors, scaffold and adaptor proteins, Ras GTPases, phospholipases, oncogenes, cyclic nucleotides, phosphoinositides, isoprenoids and steroid hormones. Offered jointly with BCHM 432. Three lecture hours per week. Fall term; D. Maurice.
PREREQUISITE: BCHM 310, or BCHM 315 and BCHM 316 and BCHM 317 for BCHM students; BCHM 310, or BCHM 315 and BCHM 316 for LISC students (or equivalent).   
EXCLUSION: BCHM 432, BCHM 431, BCHM 433, BCHM 831 , BCHM 832 , BCHM 833 , BMED 831 .   

BMED 833     Selected Topics in Mammalian Histology     
Detailed histological assessment of selected organs and tissues. Lectures and seminars. Not offered in 2022-23. 
PREREQUISITES: ANAT 215 and 216 or ANAT 311 or ANAT 309 or ANAT 831 or BMED 831.
EXCLUSION: ANAT 833    

BMED 834     Principles and Techniques in the Teaching of Anatomical Sciences     
A series of lectures and workshops illustrating modern teaching philosophy and technique specifically designed for teaching Anatomy in the Health Sciences. L.W. MacKenzie. 
EXCLUSION: ANAT 834

BMED 835     Advanced Procaryotic Structure and Function     
In depth analysis of the genetics, biochemistry, assembly and function of the major structures of the procaryotic cell. Emphasis on the experimental approaches in the current literature. (Offered in alternate years to BMED 836 and concurrently with MICR 435 with additional work required.) Fall term, two hours lecture, one hour tutorial.  Not offered in 2022-23.
EXCLUSION: MICR 835

BMED 836     Microbial Genetics     
A detailed description of the processes of heredity in bacteria including a discussion of gene structure and evolution, gene expression and its control, the exchange of genetic material in the microbial world and genetic engineering and its applications. The laboratory component will emphasize modern approaches to genetic engineering. (Offered in alternate years to BMED 835 and concurrently with MICR 436 with additional work required.)   Not offered in 2022-23.
EXCLUSION: MICR 836

BMED 840     Principles of General Pharmacology I     
Lectures, tutorial sessions, laboratory project, and self directed critical analysis of a current research area in Pharmacology. Topics include: principles of drug action, autonomic and autacoid pharmacology, and toxicology. 3 lecture hours and 3 laboratory hours. Not offered in 2022-23.
PREREQUISITE: Permission of the Graduate Program required.
EXCLUSION: PHAR 340 , PHAR 840.

BMED 841     Current Topics in Biochemistry I     
This course will focus on protein structure and function with special emphasis on membrane proteins and selected soluble protein systems. The course will consist of lectures and presentations that will be organized around specific readings from the recent literature. A portion of the course will be devoted to membrane protein structure and function. Selected examples of structural and functional studies of soluble proteins will include enzymes and inhibitors; protein protein interactions; protein engineering; high throughput identification of enzyme substrates. Some instruction will be given in homology modeling and database analysis of gene products. Three hours per week, half course lectures and seminars. Fall term;  P. Davies.
PREREQUISITE: BCHM 410 and BCHM 411 (or equivalent) and permission of coordinator.    
EXCLUSION: BCHM 841

BMED 844     Gastrointestinal Physiology     
The mechanisms and regulation of motor, secretory, digestive and absorptive functions of the gastrointestinal tract are considered. Students will be required to prepare and present reviews of original literature. Fall/winter terms.(Enrolment in both terms is required to achieve credit.) One hour lecture/week; 1 hour seminar alt. wks. M. Blennerhassett. Offered jointly with PHGY 444. Enrolment is limited.  Not offered in 2022-23.
PREREQUISITE:  PHGY 214 or equivalent.  
EXCLUSION: PHGY 444, PHGY 844

BMED 846  Advanced Biomedical Sciences
An advanced course for graduate students in which directed studies are used to examine select areas of biomedical science. Two hours seminar. Fall and/or Winter and/or Summer term. N. Magoski.
PREREQUISITE: Permission of the course coordinator required.
EXCLUSION: PHGY 836

BMED 847     Research Projects in Anatomy and Cell Biology     
An investigation into concepts and techniques in selected areas of research offered in the Department of Anatomy. Research projects carried out under the supervision of a staff member.  Logan Bale and Staff.
EXCLUSION: ANAT 847

BMED 849     Principles of General Pharmacology II     
Lectures, tutorial sessions, laboratory projects, drug literature evaluation, and self directed critical analysis of a current research area in Pharmacology. Topics include: neuropsychopharmacology, cardiovascular renal pharmacology, agents acting on the endocrine system, and chemotherapy. 3 lecture hours and 3 laboratory hours. Winter term; N. Philbrook.  Not offered in 2022-23.
PREREQUISITE: Permission of the Graduate Program required. EXCLUSION:  PHAR 450 , PHAR 850.

BMED 851     Selected Topics in Viral Pathogenesis     
The nature of selected animal virus groups and their interactions with the host in disease production with special emphasis on the pathogenesis of tumor and human immunodeficiency viruses will be considered. (Offered concurrently with MICR 451 with additional work required). Two lecture hours, two seminars hours, one tutorial hour. Winter term; C. Colpitts.
EXCLUSIONS: MICR 451, MICR 851.

BMED 852     Virus Infection and Immunity     
The molecular basis for virus pathogenesis including the host immune response to virus infection, and viral countermeasures. Emphasis will be on viral infections that result in gastrointestinal, haematological, neurological, and respiratory disease. Tutorials will focus on discussion of current and seminal literature. Offered jointly with MICR 452. Fall term; B. Banfield.  
PREREQUISITES: MICR 221, MICR 360/860 or BMED 877 or equivalents. EXCLUSIONS: MICR 452, MICR 852    

BMED 853     Cellular and Molecular Cardiovascular Sciences      
An advanced inter disciplinary course studying the anatomy, pharmacology and physiology of the cardiovascular system at the molecular and cellular level. The course is comprised of lectures, discussion and student seminars based on recent literature. 3 hour seminar. Equivalent of CRSS 456. Winter term; D.H. Maurice.
PREREQUISITE: Undergraduate degree in Life Science or equivalent or permission from department.   
EXCLUSIONS: ANAT 853 , PHAR 853 , PHGY 853 , CRSS 456.   

BMED 854     Cardiovascular Sciences      
A study of the anatomy, pharmacology and physiology of the cardiovascular system based on lectures, seminars, laboratories and selected readings (same as PHAR 854 and PHGY 854). Topics include structure function of the heart and blood vessels, mechanisms of signal transduction, drug effects on second messenger systems, the cardiac pump, integrated cardiovascular control, arterial oxygen transport, control of blood pressure and hypertension. Offered jointly with LISC 454. Additional work prescribed for graduate students. Enrolment limited. Lectures, seminars and laboratories.  Fall and Winter terms; M. Adams
PREREQUISITE: OR COREQUISITES: ANAT 311, ANAT 309 , PHAR 340/450 and PHGY 312 or their equivalent.   
EXCLUSIONS: ANAT 854 , PHAR 854 , PHGY 854 , LISC 454 .   

BMED 855     Respiratory Physiology     
An advanced course examining respiratory mechanics, gas exchange, acid base balance and the neural control of breathing. Students are required to prepare and present reviews of literature and interpret results of laboratory experiments.  2 hours lecture/seminar or 6 hours laboratory. Offered jointly with PHGY 355.  Winter  term; N. Domnik.
PREREQUISITE: A minimum of C (2.0) in PHGY 214 or equivalent.
EXCLUSION: PHGY 855 , PHGY 355

BMED 860     Fundamentals of research     
The objective of this course is to expose graduate students to the fundamental issues involved in academic research, including safety, ethics, statistics, command of the literature and drafting of a research proposal. Fall term; S. Pang.
EXCLUSION: NSCI 800  

BMED 862     Cellular techniques     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in cell culture models for biomedical and molecular sciences research. (Weight= 1.5 credit units). Winter term; D. Maurice. Not offered in 2022-23.

BMED 863     Protein and peptide analysis     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used for protein and peptide analysis involved in biomedical research. (Weight= 1.5 credit units). Winter term; G. Côté. Not offered in 2022-23.

BMED 864     Nucleic acid analysis     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used for nucleic acid analysis involved in biomedical and molecular sciences research. (Weight= 1.5 credit unit). Winter term; Y. Tse.

BMED 865     Cell imaging analysis     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used for cell imaging analysis involved in biomedical and molecular sciences research.(Weight= 1.5 credit unit.). Summer term; B. Banfield. 

BMED 866    Bioinformatics
This course provides hands on training in analytical methods for extracting and interpreting biologically relevant information from various biomedical datasets. Through a combination of lectures and labs, we will cover hypotheses driving "BIG DATA" research and computing methods for testing these hypotheses using examples of real biomedical datasets. (Offered jointly with CISC 875). Not offered in 2022-23.
EXCLUSION: CISC 875

BMED 867     In vivo laboratory techniques     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in in vivo laboratory techniques. (Weight= 1.5 credit unit.) Summer term; T. Ozolins.

BMED 868     Clinical neuroscience methods     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in clinical neuroscience methods involved in biomedical research. (Weight= 1.5 credit unit).  Not offered in 2022-23.
EXCLUSION: NSCI 868  

BMED 869     Methods in Reproduction     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used in reproductive and developmental biology involved in biomedical and molecular sciences research. (Weight= 1.5 credit unit) Fall term; C. Tayade. Not offered in 2022-23.

BMED 870     Analysis of Small Molecules     
The objective of this course is to familiarize graduate students with the principles and practice of cutting edge technologies used for the analysis of small molecules involved in biomedical and molecular research. (Weight= 1.5 credit unit).  Not offered in 2022-23.

BMED 877     Immunology     
The general principles and mechanisms of immune reaction. Immunochemical and immunobiological aspects of antibody formation and cell mediated immunity in health and disease will be considered. (Offered concurrently with MICR 360 with additional work required.)  Not offered in 2022-23. 
EXCLUSION: MICR 860

BMED 878     Microbial Pathogenesis     
A comprehensive course emphasizing the major microbial and viral groups occurring in human and animal disease. The basic mechanisms involved in host parasite interrelationships as well as current effective methodology used in their control will be studied. Fall term. N. Martin.  Not offered in 2022-23.
EXCLUSION: MICR 920

BMED 879     Advanced Bacteriology     
Advanced studies in contemporary bacteriology emphasizing important topics through analysis of the current literature in oral and written formats.Three seminar hours. Fall term; K. Jarrell. Not offered in 2022-23.
EXCLUSION: MICR 930

BMED 881     Advanced Immunology     
An advanced course emphasizing the main areas of contemporary immunology. Fall term; S. Basta.
EXCLUSION: MICR 960    

BMED 882 Proteomics and Metabolomics
‘Omics’ technologies allow the components of a living organism to be appreciated in their entirety by providing insight into gene expression, protein synthesis and function, and metabolic networking. This course builds upon concepts presented in undergraduate courses by covering the basic principles of proteomics and metabolomics and their application in the new systems biology ‘omics’ approach to scientific discovery. This course will emphasize both the methodologies used in proteomics and metabolomics, as well as their applications in both research and medical diagnostic settings.  Coursework will be completed primarily online as modules, interactive discussions, and assignments. An individual in person presentation/seminar will be required. Offered jointly with BCHM 482. PREREQUISITES: BCHM 315/3.0 and BCHM 316/3.0, or BCHM 310/9.0 or equivalent. Winter Term, R. Campbell. 
EXCLUSION: BCHM 482

BMED 889     Practicum     
EXCLUSION: ANAT 889

BMED 894 Neuroendocrinology
An in depth study of selected topics in neuroendocrinology (neural control of endocrine and autonomic function) and neuroendocrine techniques focusing on primary literature underlying critical advances over the past 40 years. Students learn to critically evaluate scientific literature. Instructional format is primarily student led seminars. (Offered odd years; jointly with PHGY 494).  Winter term; A. Ferguson. 
PREREQUISITE: PHGY 214 or equivalent. Program option.
EXCLUSION: PHGY 494

BMED 897     Research Seminars     
The objective of this course is to expose graduate students to cutting edge research and provide them the opportunity to deliver research seminars in a clear and concise fashion. This course spans a two year period. Fall, Winter, and Summer. 

BMED 898     Master's Independent Project Report     
As a component of the curriculum for the Pattern II Program in Anatomical Sciences, students will complete an independent studies project under the supervision of departmental faculty member. Students will summarize their work in a written report that will be reviewed by a committee and orally defended.
EXCLUSION: ANAT 898

BMED 899     Master's Thesis Research                
EXCLUSIONS: ANAT 899, BCHM 899, MICR 899, PHAR 899, PHGY 899

BMED 999     Ph.D. Thesis Research     
EXCLUSIONS: ANAT 999, BCHM 999, MICR 999, PHAR 999, PHGY 999