BMED 832 Molecular Basis of Cell Function
This course provides an introduction to the signaling pathways that regulate key cellular functions such as growth and motility. The biochemical and structural principles that underlie the regulation of enzyme and protein activity in cells are emphasized. Topics include protein kinases and phosphatases, ubiquitin modification, G-protein-coupled receptors, growth factor receptors, scaffold and adaptor proteins, Ras GTPases, phospholipases, oncogenes, cyclic nucleotides, phosphoinositides, isoprenoids and steroid hormones. Offered jointly with BCHM 432. Three lecture hours per week. Fall; G.P. Côté. PREREQUISITE: BCHM 310, or BCHM 315 and BCHM 316 and BCHM 317 for BCHM students; BCHM 310, or BCHM 315 and BCHM 316 for LISC students (or equivalent). EXCLUSION: BCHM 432, BCHM 431, BCHM 433, BCHM- 831*, BCHM-832*, BCHM 833*, BMED-831*.
The Department of Biomedical and Molecular Sciences (DBMS) is located in Botterell Hall, which also houses the Bracken Health Sciences library and excellent animal care facilities. Students in the DBMS graduate program will have access to infrastructure and expertise from 58 primary DBMS faculty members, which includes 4 Tier I and 3 Tier II Canada Research Council Chairs, in the Centre for Cardiac, Circulation, and Respiratory Science, the Gastrointestinal Disease Research Unit, the Centre for Neuroscience Studies, the Research Group in Reproduction, Development, and Sexual Function, the Protein Function and Discovery Facility and the Divisions of Cardiology, Gastroenterology, Emergency Medicine, Neurology and Respirology in the Faculty of Health Sciences. In addition to the unique equipment found in the laboratories of participating faculty, additional resources available to students include a common animal care facility, common autoclaves, common and individual bacterial incubators, common and individual centrifuges, common cold rooms, common confocal microscopes, common and individual fluorescent microscopes, common dark rooms, common and individual gel documentation systems, a common electron microscopy.
...take at most one BMED-based elective. Elective...courses are 3CU): CISC 832 Database Management Systems...