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PHAR 416 Xenobiotic Disposition and Toxicity Units: 3.00
An advanced study of chemical disposition and toxicity. Topics include toxicokinetics, biotransformation, metabolite-mediated toxicity, free radicals, the mechanism of action of toxicants, effects of toxicants on organ systems and a detailed examination of selected toxic agents.
NOTE BCHM, BIOL, BMCO, ELSC, and ETOX students should contact the Department for permission to enrol in this course.
NOTE BCHM, BIOL, BMCO, ELSC, and ETOX students should contact the Department for permission to enrol in this course.
Learning Hours: 120 (36 Lecture, 84 Private Study)
Requirements: Prerequisite Level 4 or above and registration in a LISC/BCHM Major or Specialization, ELSC Specialization, or BHSc program, and a CGPA of 2.5 or higher and (PHAR 370/3.0 or BCHM 310/9.0 or BCHM 316/3.0).
Offering Faculty: Faculty of Health Sciences
Course Learning Outcomes:
- Describe principles and mechanisms of toxicity.
- Explain the effects of exposure to chemicals in different situations.
- Compare and contrast mechanisms of toxicity in different target tissues.
- Consolidate knowledge to be able to critically analyze the attributes and shortcomings of peer reviewed manuscripts in the discipline of toxicology.
- Present key points related to specific topics in toxicology.