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CHEM 314  Strategies in Organic Synthesis  Units: 3.00  
One further step in mastering synthetic organic chemistry. Building on knowledge of introductory organic reactivity, essential principles underlying strategies in synthetic organic chemistry will be covered, with an emphasis on regio- and stereo-controls.
Learning Hours: 120 (36 Lecture, 12 Tutorial, 72 Private Study)  
Requirements: Prerequisite CHEM 223/3.0 or CHEM 282/3.0. Corequisite CHEM 311/3.0.  
Offering Faculty: Faculty of Arts and Science  

Course Learning Outcomes:

  1. Integrate knowledge from different functional groups, analyze their interplay, allowing to complete a reaction sequence, towards total synthesis.
  2. Plan synthetic sequences taking advantage of the regioselectivity and stereoselectivity of reactions reviewed in 2nd and 3rd year Organic Chemistry courses.
  3. Predict products of a reaction sequence, including which major regioisomer(s) and/or stereoisomer(s) are formed.
  4. Write complete reaction mechanisms, identify rate-determining step and relevant transition-state, in order to justify the outcome of a particular reaction.
  5. Research and present reactions related to carbonyl chemistry, cycloadditions, heterocyclic chemistry and radical transformations (extensions to other type of chemistry may also apply).