To understand diseases, microrobots function as minimally invasive measurement tools that let us watch and perturb biology from the inside out. Actuated by combined magnetic–acoustic fields, the microrobots designed by our lab steer into hard-to-reach sites (e.g., brain tumors, lung nodules, GI tract) and used as precision probes to map the mechanical and biochemical microenvironment in space and time. For example, microrobots are controlled to measure how and understand cancer cells are mechanically different from healthy cells; how mechanical stimulation within our skull is affecting brain tumors; and how changes in mechanical properties can indicate lung cancers [Figure adapted from Wang et al., Science Robotics 2019].

To treat diseases, microrobots represent a cutting-edge technology with transformative potential for diagnosis, treatment, and recurrence prevention. These miniature robots offer precise targeting and delivery of therapeutic agents to specific tissues or cells within the body, minimizing potential side effects and increasing treatment efficacy. Actuated by external fields, microrobots can navigate through anatomical-challenging structures and reach inaccessible areas (e.g., brain tumors). At the targeted disease region, these microrobots can be controlled to release therapeutic reagents or perform nano-scale surgery. Currently, we are working towards designing microrobots with more biocompatible materials, actuated by acoustic and magnetic combined field, with better delivery and controlled retrieval mechanisms. As research in microrobotics continues to advance, the translation of these innovative technologies from bench to bedside is poised to redefine the future of medicine. [Figure adapted from Wang et al. Science Advances 2023]

Leveraging its small size, we explore small-scale robots for applications in dental procedures and aesthetic medicine.

We current work with our industry partners to develop novel applications of microrobots, and always welcome more partners to join the force.

[Figure adapted from Nano Magazine 2023]