General Organic Chemistry II (with Virtual Laboratory)

CHEM 285/3.0


A continuation from CHEM 281/3.0 intended for students in biological sciences, and other plans taking no further courses in organic chemistry. Organic molecules and their reactions; relevance to biological systems. Illustrations using biomolecules such as carbohydrates, amino acids and proteins, lipids, and nucleic acids. The virtual laboratory provides knowledge of elementary organic syntheses.

Learning Outcomes

  • Write names of molecules from structures and vice versa. Identify and name functional groups 

  • Identify reactive sites on reagents (nucleophiles, electrophiles, acids, bases, leaving groups) 

  • Identify stereochemistry of molecules in terms of nomenclature and class of compound 

  • Predict and justify the impact of solvent and electronic effects on reactivity 

  • Predict reaction outcomes in the context of substitution and elimination reactions  

  • Add to the reactions from CHEM281 for functional group interconversions 

  • Combine functional group interconversions in more complex molecules 

  • Learn protecting group chemistry and apply to multi-step syntheses 

  • Use NMR, mass spec, and IR data to determine structures of simple compounds 

  • Explore basic experimental techniques through Labster and other lab simulations 

Textbook sections covered

Unit 1Chapter 13 - Conjugated Unsaturated Systems
Unit 2Chapter 14 - Aromatic Compounds
Unit 3Chapter 15 - Reactions of Aromatic Compounds
Unit 4Chapter 12 - Alcohols from Carbonyl Compounds
Unit 5Chapter 10 - Radical Reactions
Unit 6Chapter 16 - Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl Group
Unit 7Chapter 17 - Aldehydes and Ketones II: Enols and Enolates
Unit 8Chapter 18 - Carboxylic Acids and their Derivatives
Unit 9Chapter 19 - Synthesis and Reactions of Beta Dicarbonyl Compounds
Unit 10Chapter 20 - Amines
Unit 11Chapter 20 - Carbohydrates
Unit 12Chapter 23 - Lipids
Unit 13Chapter 24 - Amino Acids and Proteins


Summer (July–August) 2023
Course Dates
Exam Dates (if applicable)
Delivery Mode


20% - WileyPLUS 
20% - Virtual Labs
20% - Midterm Exam 
40% - Proctored Final Exam

Students require a 50% overall to pass the course totalled from all course components and must attempt all assessments of significant course weighting.

** Evaluation Subject to Change **

Live Sessions

This course has optional live sessions (e.g. webinars, synchronous activities).

Web-based Tutorials

Regular, interactive, recorded web-based tutorials (with screen sharing and virtual whiteboard) will be held between student groups and tutors/instructor to keep students to milestone syllabus achievements. The tutorials will be both topic-based and free-form in order for questions to be asked and solved. Tutorials will be held every week.

Virtual Office Hours and onQ Discussion Forum

Virtual office hours (recorded) with the instructor/TAs will be available at least once a week using web-based video chat functionality. The onQ discussion forum will be available every day. A response to questions posted in the onQ discussion forum is guaranteed within 24 hours.

Proctored Exams

If a student is enrolled in ONLY online courses (section 700), they may choose either of the following options to write the exam:

  • Write the final exam online: you will write in onQ with Examity proctoring. A $100 online exam fee will be charged to your SOLUS account.  
  • Write the final exam in-person: you will write on Queen’s campus in Kingston. You will not be charged an extra fee to write on campus. 

If a student is enrolled in ANY in-person courses (section 001, 002, etc), you MUST write all your final exams in-person on Queen’s campus, including for an online course. You may not choose to write your exams online. 

Location and Timing of Final Exams

Once the exam schedule has been finalized the exam date will be posted on your SOLUS account. The exam dates for each Term are listed in the Academic Calendar. Student exam schedules for the Fall Term are posted via SOLUS immediately prior to the Thanksgiving holiday; for the Winter Term they are posted on the Friday before Reading Week, and for the Summer Term they are individually noted on the Arts and Science Online syllabi. Students should delay finalizing any travel plans until after the examination schedule has been posted. Exams will not be moved or deferred to accommodate employment, travel/holiday plans or flight reservations. 

Textbook and Materials


  • CHEM 282 Virtual Lab and Guide (provided)

ASO reserves the right to make changes to the required material list as received by the instructor before the course starts. Please refer to the Campus Bookstore website at to obtain the most up-to-date list of required materials for this course before purchasing them.

Textbook Package


  • Organic Chemistry, Solomons and Fryhle, 12th ed. (Wiley)
  • OrganicView CD
  • Accompanying Study Guide and Solutions Manual Molecular Models
  • WileyPLUS online code to access digital textbook (may be purchased as part of textbook package or separately)

The following materials are available in the Queen's onQ online course site:


  • An electronic virtual lab guide will be provided

Course Guide

The Course Guide contains the overall directions and lecture notes needed to complete the course. It is available online in the onQ virtual learning environment. Beginning the first day of term, students registered in the course will be able to access course materials in a format suitable for online reading or printing.

Recommended Materials

  • Organic Laboratory Techniques, Fessenden, Fessenden and Feist, 3rd ed. (Brooks/Cole)
  • Organic Chemistry I as a Second Language: Translating the Basic Concepts, David R. Klein.
    • Wiley E-Text
      • Organic Chemistry I As a Second Language: First Semester Topics, 3rd Edition 
        ISBN : 978-1-118-20377-4, 400 pages, August 2011, ©2012, CDN $31.00   BUY
    • Paperback
      • Organic Chemistry I As a Second Language: First Semester Topics, 3rd Edition
        ISBN : 978-1-118-01040-2, 400 pages, June 2011, ©2012, CDN $55.95   BUY

Time Commitment

Students can expect to spend approximately 16.5 - 18 hours a week (108 hours total) in study/practice and online activity for this course. 

Additional Information

NOTE: Life Sciences Honours students should not enrol in this course.